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Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis.
Garcia-Recio S, Hinoue T, Wheeler GL, Kelly BJ, Garrido-Castro AC, Pascual T, De Cubas AA, Xia Y, Felsheim BM, McClure MB, Rajkovic A, Karaesmen E, Smith MA, Fan C, Ericsson PIG, Sanders ME, Creighton CJ, Bowen J, Leraas K, Burns RT, Coppens S, Wheless A, Rezk S, Garrett AL, Parker JS, Foy KK, Shen H, Park BH, Krop I, Anders C, Gastier-Foster J, Rimawi MF, Nanda R, Lin NU, Isaacs C, Marcom PK, Storniolo AM, Couch FJ, Chandran U, Davis M, Silverstein J, Ropelewski A, Liu MC, Hilsenbeck SG, Norton L, Richardson AL, Symmans WF, Wolff AC, Davidson NE, Carey LA, Lee AV, Balko JM, Hoadley KA, Laird PW, Mardis ER, King TA; AURORA US Network; Perou CM. Garcia-Recio S, et al. Among authors: shen h. Nat Cancer. 2023 Jan;4(1):128-147. doi: 10.1038/s43018-022-00491-x. Epub 2022 Dec 30. Nat Cancer. 2023. PMID: 36585450 Free PMC article.
In epigenetic therapy, less is more.
Shen H, Laird PW. Shen H, et al. Cell Stem Cell. 2012 Apr 6;10(4):353-4. doi: 10.1016/j.stem.2012.03.012. Cell Stem Cell. 2012. PMID: 22482500 Free article.
Integrated genomic characterization of endometrial carcinoma.
Cancer Genome Atlas Research Network; Kandoth C, Schultz N, Cherniack AD, Akbani R, Liu Y, Shen H, Robertson AG, Pashtan I, Shen R, Benz CC, Yau C, Laird PW, Ding L, Zhang W, Mills GB, Kucherlapati R, Mardis ER, Levine DA. Cancer Genome Atlas Research Network, et al. Among authors: shen h, shen r. Nature. 2013 May 2;497(7447):67-73. doi: 10.1038/nature12113. Nature. 2013. PMID: 23636398 Free PMC article.
The Cancer Genome Atlas Pan-Cancer analysis project.
Cancer Genome Atlas Research Network; Weinstein JN, Collisson EA, Mills GB, Shaw KR, Ozenberger BA, Ellrott K, Shmulevich I, Sander C, Stuart JM. Cancer Genome Atlas Research Network, et al. Nat Genet. 2013 Oct;45(10):1113-20. doi: 10.1038/ng.2764. Nat Genet. 2013. PMID: 24071849 Free PMC article.
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