Shen F - Search Results

1

Combined Blockade of TNF-α and IL-17A Alleviates Progression of Collagen-Induced Arthritis without Causing Serious Infections in Mice.

Shen F, Verma AH, Volk A, Jones B, Coleman BM, Loza MJ, Malaviya R, Moore B, Weinstock D, Elloso MM, Gaffen SL, Ort T. Shen F, et al. J Immunol. 2019 Apr 1;202(7):2017-2026. doi: 10.4049/jimmunol.1801436. Epub 2019 Feb 11. J Immunol. 2019. PMID: 30745461 Free PMC article.

2

Characterization of concurrent target suppression by JNJ-61178104, a bispecific antibody against human tumor necrosis factor and interleukin-17A.

Zheng S, Shen F, Jones B, Fink D, Geist B, Nnane I, Zhou Z, Hall J, Malaviya R, Ort T, Wang W. Zheng S, et al. Among authors: shen f. MAbs. 2020 Jan-Dec;12(1):1770018. doi: 10.1080/19420862.2020.1770018. MAbs. 2020. PMID: 32544369 Free PMC article.

3

A Cryo-pulverization Protocol for Processing Mouse Paws to Evaluate Molecular Pathways of Tissue Inflammation in a Collagen Induced Arthritis Model.

Jones B, Hitchcock S, Loza M, Malaviya R, Ort T, Shen F. Jones B, et al. Among authors: shen f. J Vis Exp. 2019 Oct 30;(152). doi: 10.3791/60229. J Vis Exp. 2019. PMID: 31736486

4

Pharmacokinetics, Pharmacodynamics, Immunogenicity, Safety, and Tolerability of JNJ-61178104, a Novel Tumor Necrosis Factor-Alpha and Interleukin-17A Bispecific Antibody, in Healthy Subjects.

Akpalu DE, Frederick B, Nnane IP, Yao Z, Shen F, Ort T, Fink D, Dogmanits S, Raible D, Sharma A, Xu Z. Akpalu DE, et al. Among authors: shen f. J Clin Pharmacol. 2019 Jul;59(7):968-978. doi: 10.1002/jcph.1393. Epub 2019 Feb 18. J Clin Pharmacol. 2019. PMID: 30776134 Clinical Trial.

5

Interleukin-17 regulates expression of the CXC chemokine LIX/CXCL5 in osteoblasts: implications for inflammation and neutrophil recruitment.

Ruddy MJ, Shen F, Smith JB, Sharma A, Gaffen SL. Ruddy MJ, et al. Among authors: shen f. J Leukoc Biol. 2004 Jul;76(1):135-44. doi: 10.1189/jlb.0204065. Epub 2004 Apr 23. J Leukoc Biol. 2004. PMID: 15107456

6

Cytokines link osteoblasts and inflammation: microarray analysis of interleukin-17- and TNF-alpha-induced genes in bone cells.

Shen F, Ruddy MJ, Plamondon P, Gaffen SL. Shen F, et al. J Leukoc Biol. 2005 Mar;77(3):388-99. doi: 10.1189/jlb.0904490. Epub 2004 Dec 10. J Leukoc Biol. 2005. PMID: 15591425

7

Evidence for ligand-independent multimerization of the IL-17 receptor.

Kramer JM, Yi L, Shen F, Maitra A, Jiao X, Jin T, Gaffen SL. Kramer JM, et al. Among authors: shen f. J Immunol. 2006 Jan 15;176(2):711-5. doi: 10.4049/jimmunol.176.2.711. J Immunol. 2006. PMID: 16393951 Free PMC article.

8

Structure-function relationships in the IL-17 receptor: implications for signal transduction and therapy.

Shen F, Gaffen SL. Shen F, et al. Cytokine. 2008 Feb;41(2):92-104. doi: 10.1016/j.cyto.2007.11.013. Epub 2008 Jan 4. Cytokine. 2008. PMID: 18178098 Free PMC article. Review.

9

The IL-17 cytokine family.

Gaffen SL, Kramer JM, Yu JJ, Shen F. Gaffen SL, et al. Among authors: shen f. Vitam Horm. 2006;74:255-82. doi: 10.1016/S0083-6729(06)74010-9. Vitam Horm. 2006. PMID: 17027518 Review.

10

Differential role for c-Rel and C/EBPbeta/delta in TLR-mediated induction of proinflammatory cytokines.

Lu YC, Kim I, Lye E, Shen F, Suzuki N, Suzuki S, Gerondakis S, Akira S, Gaffen SL, Yeh WC, Ohashi PS. Lu YC, et al. Among authors: shen f. J Immunol. 2009 Jun 1;182(11):7212-21. doi: 10.4049/jimmunol.0802971. J Immunol. 2009. PMID: 19454718 Free PMC article.

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