Shen DD - Search Results

1

LSD1 deletion decreases exosomal PD-L1 and restores T-cell response in gastric cancer.

Shen DD, Pang JR, Bi YP, Zhao LF, Li YR, Zhao LJ, Gao Y, Wang B, Wang N, Wei L, Guo H, Liu HM, Zheng YC. Shen DD, et al. Mol Cancer. 2022 Mar 16;21(1):75. doi: 10.1186/s12943-022-01557-1. Mol Cancer. 2022. PMID: 35296335 Free PMC article.

2

1,2,3-Triazole-Dithiocarbamate Hybrids, a Group of Novel Cell Active SIRT1 Inhibitors.

Zheng YC, Wang LZ, Zhao LJ, Zhao LJ, Zhan QN, Ma JL, Zhang B, Wang MM, Wang ZR, Li JF, Liu Y, Chen ZS, Shen DD, Liu XQ, Ren M, Lv WL, Zhao W, Duan YC, Liu HM. Zheng YC, et al. Among authors: shen dd. Cell Physiol Biochem. 2016;38(1):185-93. doi: 10.1159/000438620. Epub 2016 Jan 20. Cell Physiol Biochem. 2016. PMID: 26784898 Free article.

3

Design, synthesis and biological evaluation of [1,2,4]triazolo[1,5-a]pyrimidines as potent lysine specific demethylase 1 (LSD1/KDM1A) inhibitors.

Wang S, Zhao LJ, Zheng YC, Shen DD, Miao EF, Qiao XP, Zhao LJ, Liu Y, Huang R, Yu B, Liu HM. Wang S, et al. Among authors: shen dd. Eur J Med Chem. 2017 Jan 5;125:940-951. doi: 10.1016/j.ejmech.2016.10.021. Epub 2016 Oct 14. Eur J Med Chem. 2017. PMID: 27769034

4

Baicalin, a natural LSD1 inhibitor.

Zheng YC, Shen DD, Ren M, Liu XQ, Wang ZR, Liu Y, Zhang QN, Zhao LJ, Zhao LJ, Ma JL, Yu B, Liu HM. Zheng YC, et al. Among authors: shen dd. Bioorg Chem. 2016 Dec;69:129-131. doi: 10.1016/j.bioorg.2016.10.004. Epub 2016 Oct 11. Bioorg Chem. 2016. PMID: 27814566

5

Discovery of resveratrol derivatives as novel LSD1 inhibitors: Design, synthesis and their biological evaluation.

Duan YC, Guan YY, Zhai XY, Ding LN, Qin WP, Shen DD, Liu XQ, Sun XD, Zheng YC, Liu HM. Duan YC, et al. Among authors: shen dd. Eur J Med Chem. 2017 Jan 27;126:246-258. doi: 10.1016/j.ejmech.2016.11.035. Epub 2016 Nov 16. Eur J Med Chem. 2017. PMID: 27888721

6

Development of formaldehyde dehydrogenase-coupled assay and antibody-based assays for ALKBH5 activity evaluation.

Shen DD, Suo FZ, Song QM, Chang J, Zhang T, Hong JJ, Zheng YC, Liu HM. Shen DD, et al. J Pharm Biomed Anal. 2019 Jan 5;162:9-15. doi: 10.1016/j.jpba.2018.09.018. Epub 2018 Sep 7. J Pharm Biomed Anal. 2019. PMID: 30219599

7

Development of Highly Potent, Selective, and Cellular Active Triazolo[1,5- a]pyrimidine-Based Inhibitors Targeting the DCN1-UBC12 Protein-Protein Interaction.

Wang S, Zhao L, Shi XJ, Ding L, Yang L, Wang ZZ, Shen D, Tang K, Li XJ, Mamun M, Li H, Yu B, Zheng YC, Wang S, Liu HM. Wang S, et al. J Med Chem. 2019 Mar 14;62(5):2772-2797. doi: 10.1021/acs.jmedchem.9b00113. Epub 2019 Mar 4. J Med Chem. 2019. PMID: 30803229

8

Development of the triazole-fused pyrimidine derivatives as highly potent and reversible inhibitors of histone lysine specific demethylase 1 (LSD1/KDM1A).

Li Z, Ding L, Li Z, Wang Z, Suo F, Shen D, Zhao T, Sun X, Wang J, Liu Y, Ma L, Zhao B, Geng P, Yu B, Zheng Y, Liu H. Li Z, et al. Acta Pharm Sin B. 2019 Jul;9(4):794-808. doi: 10.1016/j.apsb.2019.01.001. Epub 2019 Jan 5. Acta Pharm Sin B. 2019. PMID: 31384539 Free PMC article.

9

Natural protoberberine alkaloids, identified as potent selective LSD1 inhibitors, induce AML cell differentiation.

Li ZR, Suo FZ, Guo YJ, Cheng HF, Niu SH, Shen DD, Zhao LJ, Liu ZZ, Maa M, Yu B, Zheng YC, Liu HM. Li ZR, et al. Among authors: shen dd. Bioorg Chem. 2020 Apr;97:103648. doi: 10.1016/j.bioorg.2020.103648. Epub 2020 Feb 3. Bioorg Chem. 2020. PMID: 32065882

10

Down-Regulation of USP8 Suppresses HER-3 Positive Gastric Cancer Cells Proliferation.

Sun J, Shen D, Gao Y, Zheng Y, Zhao L, Maa M, Liu H, Chen X. Sun J, et al. Onco Targets Ther. 2020 Aug 11;13:7973-7984. doi: 10.2147/OTT.S264108. eCollection 2020. Onco Targets Ther. 2020. PMID: 32848421 Free PMC article.

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