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Docosahexaenoic acid supplementation alters key properties of cardiac mitochondria and modestly attenuates development of left ventricular dysfunction in pressure overload-induced heart failure.
Dabkowski ER, O'Connell KA, Xu W, Ribeiro RF Jr, Hecker PA, Shekar KC, Daneault C, Des Rosiers C, Stanley WC. Dabkowski ER, et al. Among authors: shekar kc. Cardiovasc Drugs Ther. 2013 Dec;27(6):499-510. doi: 10.1007/s10557-013-6487-4. Cardiovasc Drugs Ther. 2013. PMID: 24013804 Free PMC article.
Cardiac mitochondrial proteome dynamics with heavy water reveals stable rate of mitochondrial protein synthesis in heart failure despite decline in mitochondrial oxidative capacity.
Shekar KC, Li L, Dabkowski ER, Xu W, Ribeiro RF Jr, Hecker PA, Recchia FA, Sadygov RG, Willard B, Kasumov T, Stanley WC. Shekar KC, et al. J Mol Cell Cardiol. 2014 Oct;75:88-97. doi: 10.1016/j.yjmcc.2014.06.014. Epub 2014 Jul 1. J Mol Cell Cardiol. 2014. PMID: 24995939 Free PMC article.
Glucose 6-phosphate dehydrogenase deficiency increases redox stress and moderately accelerates the development of heart failure.
Hecker PA, Lionetti V, Ribeiro RF Jr, Rastogi S, Brown BH, O'Connell KA, Cox JW, Shekar KC, Gamble DM, Sabbah HN, Leopold JA, Gupte SA, Recchia FA, Stanley WC. Hecker PA, et al. Among authors: shekar kc. Circ Heart Fail. 2013 Jan;6(1):118-26. doi: 10.1161/CIRCHEARTFAILURE.112.969576. Epub 2012 Nov 20. Circ Heart Fail. 2013. PMID: 23170010 Free PMC article.
Enhanced resistance to permeability transition in interfibrillar cardiac mitochondria in dogs: effects of aging and long-term aldosterone infusion.
Asemu G, O'Connell KA, Cox JW, Dabkowski ER, Xu W, Ribeiro RF Jr, Shekar KC, Hecker PA, Rastogi S, Sabbah HN, Hoppel CL, Stanley WC. Asemu G, et al. Among authors: shekar kc. Am J Physiol Heart Circ Physiol. 2013 Feb 15;304(4):H514-28. doi: 10.1152/ajpheart.00674.2012. Epub 2012 Dec 15. Am J Physiol Heart Circ Physiol. 2013. PMID: 23241318 Free PMC article.
Effects of glucose-6-phosphate dehydrogenase deficiency on the metabolic and cardiac responses to obesogenic or high-fructose diets.
Hecker PA, Mapanga RF, Kimar CP, Ribeiro RF Jr, Brown BH, O'Connell KA, Cox JW, Shekar KC, Asemu G, Essop MF, Stanley WC. Hecker PA, et al. Among authors: shekar kc. Am J Physiol Endocrinol Metab. 2012 Oct 15;303(8):E959-72. doi: 10.1152/ajpendo.00202.2012. Epub 2012 Jul 24. Am J Physiol Endocrinol Metab. 2012. PMID: 22829586 Free PMC article.
Evaluation of docosahexaenoic acid in a dog model of hypertension induced left ventricular hypertrophy.
Stanley WC, Cox JW, Asemu G, O'Connell KA, Dabkowski ER, Xu W, Ribeiro RF Jr, Shekar KC, Hoag SW, Rastogi S, Sabbah HN, Daneault C, des Rosiers C. Stanley WC, et al. Among authors: shekar kc. J Cardiovasc Transl Res. 2013 Dec;6(6):1000-10. doi: 10.1007/s12265-013-9511-y. Epub 2013 Sep 25. J Cardiovasc Transl Res. 2013. PMID: 24065618 Free PMC article.
Assessment of cardiac proteome dynamics with heavy water: slower protein synthesis rates in interfibrillar than subsarcolemmal mitochondria.
Kasumov T, Dabkowski ER, Shekar KC, Li L, Ribeiro RF Jr, Walsh K, Previs SF, Sadygov RG, Willard B, Stanley WC. Kasumov T, et al. Among authors: shekar kc. Am J Physiol Heart Circ Physiol. 2013 May;304(9):H1201-14. doi: 10.1152/ajpheart.00933.2012. Epub 2013 Mar 1. Am J Physiol Heart Circ Physiol. 2013. PMID: 23457012 Free PMC article.
Early Effects of Prolonged Cardiac Arrest and Ischemic Postconditioning during Cardiopulmonary Resuscitation on Cardiac and Brain Mitochondrial Function in Pigs.
Matsuura TR, Bartos JA, Tsangaris A, Shekar KC, Olson MD, Riess ML, Bienengraeber M, Aufderheide TP, Neumar RW, Rees JN, McKnite SH, Dikalova AE, Dikalov SI, Douglas HF, Yannopoulos D. Matsuura TR, et al. Among authors: shekar kc. Resuscitation. 2017 Jul;116:8-15. doi: 10.1016/j.resuscitation.2017.03.033. Epub 2017 Apr 10. Resuscitation. 2017. PMID: 28408349 Free PMC article.
21 results