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Page 1
Macrophages in atherosclerosis: a dynamic balance.
Moore KJ, Sheedy FJ, Fisher EA. Moore KJ, et al. Among authors: sheedy fj. Nat Rev Immunol. 2013 Oct;13(10):709-21. doi: 10.1038/nri3520. Epub 2013 Sep 2. Nat Rev Immunol. 2013. PMID: 23995626 Free PMC article. Review.
Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides.
Rayner KJ, Esau CC, Hussain FN, McDaniel AL, Marshall SM, van Gils JM, Ray TD, Sheedy FJ, Goedeke L, Liu X, Khatsenko OG, Kaimal V, Lees CJ, Fernandez-Hernando C, Fisher EA, Temel RE, Moore KJ. Rayner KJ, et al. Among authors: sheedy fj. Nature. 2011 Oct 19;478(7369):404-7. doi: 10.1038/nature10486. Nature. 2011. PMID: 22012398 Free PMC article.
CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation.
Sheedy FJ, Grebe A, Rayner KJ, Kalantari P, Ramkhelawon B, Carpenter SB, Becker CE, Ediriweera HN, Mullick AE, Golenbock DT, Stuart LM, Latz E, Fitzgerald KA, Moore KJ. Sheedy FJ, et al. Nat Immunol. 2013 Aug;14(8):812-20. doi: 10.1038/ni.2639. Epub 2013 Jun 30. Nat Immunol. 2013. PMID: 23812099 Free PMC article.
Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity.
Ramkhelawon B, Hennessy EJ, Ménager M, Ray TD, Sheedy FJ, Hutchison S, Wanschel A, Oldebeken S, Geoffrion M, Spiro W, Miller G, McPherson R, Rayner KJ, Moore KJ. Ramkhelawon B, et al. Among authors: sheedy fj. Nat Med. 2014 Apr;20(4):377-84. doi: 10.1038/nm.3467. Epub 2014 Mar 2. Nat Med. 2014. PMID: 24584118 Free PMC article.
MicroRNA-33-dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis.
Ouimet M, Ediriweera HN, Gundra UM, Sheedy FJ, Ramkhelawon B, Hutchison SB, Rinehold K, van Solingen C, Fullerton MD, Cecchini K, Rayner KJ, Steinberg GR, Zamore PD, Fisher EA, Loke P, Moore KJ. Ouimet M, et al. Among authors: sheedy fj. J Clin Invest. 2015 Oct 26;125(12):4334-48. doi: 10.1172/JCI81676. J Clin Invest. 2015. PMID: 26517695 Free PMC article.
Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism.
Ouimet M, Koster S, Sakowski E, Ramkhelawon B, van Solingen C, Oldebeken S, Karunakaran D, Portal-Celhay C, Sheedy FJ, Ray TD, Cecchini K, Zamore PD, Rayner KJ, Marcel YL, Philips JA, Moore KJ. Ouimet M, et al. Among authors: sheedy fj. Nat Immunol. 2016 Jun;17(6):677-86. doi: 10.1038/ni.3434. Epub 2016 Apr 18. Nat Immunol. 2016. PMID: 27089382 Free PMC article.
Mycobacterium tuberculosis Limits Host Glycolysis and IL-1β by Restriction of PFK-M via MicroRNA-21.
Hackett EE, Charles-Messance H, O'Leary SM, Gleeson LE, Muñoz-Wolf N, Case S, Wedderburn A, Johnston DGW, Williams MA, Smyth A, Ouimet M, Moore KJ, Lavelle EC, Corr SC, Gordon SV, Keane J, Sheedy FJ. Hackett EE, et al. Among authors: sheedy fj. Cell Rep. 2020 Jan 7;30(1):124-136.e4. doi: 10.1016/j.celrep.2019.12.015. Cell Rep. 2020. PMID: 31914380 Free PMC article.
von Willebrand factor links primary hemostasis to innate immunity.
Drakeford C, Aguila S, Roche F, Hokamp K, Fazavana J, Cervantes MP, Curtis AM, Hawerkamp HC, Dhami SPS, Charles-Messance H, Hackett EE, Chion A, Ward S, Ahmad A, Schoen I, Breen E, Keane J, Murphy R, Preston RJS, O'Sullivan JM, Sheedy FJ, Fallon P, O'Donnell JS. Drakeford C, et al. Among authors: sheedy fj. Nat Commun. 2022 Nov 3;13(1):6320. doi: 10.1038/s41467-022-33796-7. Nat Commun. 2022. PMID: 36329021 Free PMC article.
39 results