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Vaccines and therapeutics for immunocompromised patients with COVID-19.
Shoham S, Batista C, Ben Amor Y, Ergonul O, Hassanain M, Hotez P, Kang G, Kim JH, Lall B, Larson HJ, Naniche D, Sheahan T, Strub-Wourgaft N, Sow SO, Wilder-Smith A, Yadav P, Bottazzi ME; Lancet Commission on COVID-19 Vaccines and Therapeutics Task Force. Shoham S, et al. Among authors: sheahan t. EClinicalMedicine. 2023 May;59:101965. doi: 10.1016/j.eclinm.2023.101965. Epub 2023 Apr 12. EClinicalMedicine. 2023. PMID: 37070102 Free PMC article. Review.
Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid.
Iserman C, Roden CA, Boerneke MA, Sealfon RSG, McLaughlin GA, Jungreis I, Fritch EJ, Hou YJ, Ekena J, Weidmann CA, Theesfeld CL, Kellis M, Troyanskaya OG, Baric RS, Sheahan TP, Weeks KM, Gladfelter AS. Iserman C, et al. Mol Cell. 2020 Dec 17;80(6):1078-1091.e6. doi: 10.1016/j.molcel.2020.11.041. Epub 2020 Nov 27. Mol Cell. 2020. PMID: 33290746 Free PMC article.
A human monoclonal antibody targeting scavenger receptor class B type I precludes hepatitis C virus infection and viral spread in vitro and in vivo.
Meuleman P, Catanese MT, Verhoye L, Desombere I, Farhoudi A, Jones CT, Sheahan T, Grzyb K, Cortese R, Rice CM, Leroux-Roels G, Nicosia A. Meuleman P, et al. Among authors: sheahan t. Hepatology. 2012 Feb;55(2):364-72. doi: 10.1002/hep.24692. Epub 2011 Dec 16. Hepatology. 2012. PMID: 21953761 Free PMC article.
Hypergraph models of biological networks to identify genes critical to pathogenic viral response.
Feng S, Heath E, Jefferson B, Joslyn C, Kvinge H, Mitchell HD, Praggastis B, Eisfeld AJ, Sims AC, Thackray LB, Fan S, Walters KB, Halfmann PJ, Westhoff-Smith D, Tan Q, Menachery VD, Sheahan TP, Cockrell AS, Kocher JF, Stratton KG, Heller NC, Bramer LM, Diamond MS, Baric RS, Waters KM, Kawaoka Y, McDermott JE, Purvine E. Feng S, et al. BMC Bioinformatics. 2021 May 29;22(1):287. doi: 10.1186/s12859-021-04197-2. BMC Bioinformatics. 2021. PMID: 34051754 Free PMC article.
Remdesivir potently inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice.
Pruijssers AJ, George AS, Schäfer A, Leist SR, Gralinksi LE, Dinnon KH, Yount BL, Agostini ML, Stevens LJ, Chappell JD, Lu X, Hughes TM, Gully K, Martinez DR, Brown AJ, Graham RL, Perry JK, Du Pont V, Pitts J, Ma B, Babusis D, Murakami E, Feng JY, Bilello JP, Porter DP, Cihlar T, Baric RS, Denison MR, Sheahan TP. Pruijssers AJ, et al. Among authors: sheahan tp. bioRxiv [Preprint]. 2020 Apr 27:2020.04.27.064279. doi: 10.1101/2020.04.27.064279. bioRxiv. 2020. PMID: 32511392 Free PMC article. Updated. Preprint.
132 results