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Inhibiting glucosylceramide synthase exacerbates cisplatin-induced acute kidney injury.
Dupre TV, Doll MA, Shah PP, Sharp CN, Siow D, Megyesi J, Shayman J, Bielawska A, Bielawski J, Beverly LJ, Hernandez-Corbacho M, Clarke CJ, Snider AJ, Schnellmann RG, Obeid LM, Hannun YA, Siskind LJ. Dupre TV, et al. Among authors: shayman j. J Lipid Res. 2017 Jul;58(7):1439-1452. doi: 10.1194/jlr.M076745. Epub 2017 May 10. J Lipid Res. 2017. PMID: 28490444 Free PMC article.
Under conditions of high ceramide generation, data suggest that metabolism of ceramides to glucosylceramides buffers kidney ceramides and helps attenuate kidney injury.-Dupre, T. V., M. A. Doll, P. P. Shah, C. N. Sharp, D. Siow, J. Megyesi, J. Shayman, A. Bie …
Under conditions of high ceramide generation, data suggest that metabolism of ceramides to glucosylceramides buffers kidney ceramides and he …
Improved inhibitors of glucosylceramide synthase.
Abe A, Inokuchi J, Jimbo M, Shimeno H, Nagamatsu A, Shayman JA, Shukla GS, Radin NS. Abe A, et al. Among authors: shayman ja. J Biochem. 1992 Feb;111(2):191-6. doi: 10.1093/oxfordjournals.jbchem.a123736. J Biochem. 1992. PMID: 1533217 Free article.
Improved inhibitors of glucosylceramide synthase.
Lee L, Abe A, Shayman JA. Lee L, et al. Among authors: shayman ja. J Biol Chem. 1999 May 21;274(21):14662-9. doi: 10.1074/jbc.274.21.14662. J Biol Chem. 1999. PMID: 10329660 Free article.
164 results