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Page 1
Personalized Detection of Circulating Tumor DNA Antedates Breast Cancer Metastatic Recurrence.
Coombes RC, Page K, Salari R, Hastings RK, Armstrong A, Ahmed S, Ali S, Cleator S, Kenny L, Stebbing J, Rutherford M, Sethi H, Boydell A, Swenerton R, Fernandez-Garcia D, Gleason KLT, Goddard K, Guttery DS, Assaf ZJ, Wu HT, Natarajan P, Moore DA, Primrose L, Dashner S, Tin AS, Balcioglu M, Srinivasan R, Shchegrova SV, Olson A, Hafez D, Billings P, Aleshin A, Rehman F, Toghill BJ, Hills A, Louie MC, Lin CJ, Zimmermann BG, Shaw JA. Coombes RC, et al. Among authors: shaw ja. Clin Cancer Res. 2019 Jul 15;25(14):4255-4263. doi: 10.1158/1078-0432.CCR-18-3663. Epub 2019 Apr 16. Clin Cancer Res. 2019. PMID: 30992300
The presence of disseminated tumour cells in the bone marrow is inversely related to circulating free DNA in plasma in breast cancer dormancy.
Payne RE, Hava NL, Page K, Blighe K, Ward B, Slade M, Brown J, Guttery DS, Zaidi SA, Stebbing J, Jacob J, Yagüe E, Shaw JA, Coombes RC. Payne RE, et al. Among authors: shaw ja. Br J Cancer. 2012 Jan 17;106(2):375-82. doi: 10.1038/bjc.2011.537. Epub 2011 Dec 13. Br J Cancer. 2012. PMID: 22166803 Free PMC article.
Longitudinal whole-exome sequencing of cell-free DNA for tracking the co-evolutionary tumor and immune evasion dynamics: longitudinal data from a single patient.
Hastings RK, Openshaw MR, Vazquez M, Moreno-Cardenas AB, Fernandez-Garcia D, Martinson L, Kulbicki K, Primrose L, Guttery DS, Page K, Toghill B, Richards C, Thomas A, Tabernero J, Coombes RC, Ahmed S, Toledo RA, Shaw JA. Hastings RK, et al. Among authors: shaw ja. Ann Oncol. 2021 May;32(5):681-684. doi: 10.1016/j.annonc.2021.02.007. Epub 2021 Feb 18. Ann Oncol. 2021. PMID: 33609721 Free article. No abstract available.
Prevalence of ctDNA in early screen-detected breast cancers using highly sensitive and specific dual molecular barcoded personalised mutation assays.
Page K, Martinson LJ, Hastings RK, Fernandez-Garcia D, Gleason KLT, Gray MC, Rushton AJ, Goddard K, Guttery DS, Stebbing J, Coombes RC, Shaw JA. Page K, et al. Among authors: shaw ja. Ann Oncol. 2021 Aug;32(8):1057-1060. doi: 10.1016/j.annonc.2021.04.018. Epub 2021 Apr 29. Ann Oncol. 2021. PMID: 33932505 Free article. No abstract available.
NEOCENT: a randomised feasibility and translational study comparing neoadjuvant endocrine therapy with chemotherapy in ER-rich postmenopausal primary breast cancer.
Palmieri C, Cleator S, Kilburn LS, Kim SB, Ahn SH, Beresford M, Gong G, Mansi J, Mallon E, Reed S, Mousa K, Fallowfield L, Cheang M, Morden J, Page K, Guttery DS, Rghebi B, Primrose L, Shaw JA, Thompson AM, Bliss JM, Coombes RC. Palmieri C, et al. Among authors: shaw ja. Breast Cancer Res Treat. 2014 Dec;148(3):581-90. doi: 10.1007/s10549-014-3183-4. Epub 2014 Nov 14. Breast Cancer Res Treat. 2014. PMID: 25395314 Clinical Trial.
LMTK3 is implicated in endocrine resistance via multiple signaling pathways.
Stebbing J, Filipovic A, Lit LC, Blighe K, Grothey A, Xu Y, Miki Y, Chow LW, Coombes RC, Sasano H, Shaw JA, Giamas G. Stebbing J, et al. Among authors: shaw ja. Oncogene. 2013 Jul 11;32(28):3371-80. doi: 10.1038/onc.2012.343. Epub 2012 Aug 6. Oncogene. 2013. PMID: 22869149
An open-label study of lapatinib in women with HER-2-negative early breast cancer: the lapatinib pre-surgical study (LPS study).
Coombes RC, Tat T, Miller ML, Reise JA, Mansi JL, Hadjiminas DJ, Shousha S, Elsheikh SE, Lam EW, Horimoto Y, El-Bahrawy M, Aboagye EO, Contractor KB, Shaw JA, Walker RA, Marconell MH, Palmieri C, Stebbing J. Coombes RC, et al. Among authors: shaw ja. Ann Oncol. 2013 Apr;24(4):924-30. doi: 10.1093/annonc/mds594. Epub 2012 Dec 11. Ann Oncol. 2013. PMID: 23233650 Free article. Clinical Trial.
560 results