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Mechanism of NMDA receptor channel block by MK-801 and memantine.
Song X, Jensen MØ, Jogini V, Stein RA, Lee CH, Mchaourab HS, Shaw DE, Gouaux E. Song X, et al. Among authors: shaw de. Nature. 2018 Apr;556(7702):515-519. doi: 10.1038/s41586-018-0039-9. Epub 2018 Apr 18. Nature. 2018. PMID: 29670280 Free PMC article.
Mechanism of Na+/H+ antiporting.
Arkin IT, Xu H, Jensen MØ, Arbely E, Bennett ER, Bowers KJ, Chow E, Dror RO, Eastwood MP, Flitman-Tene R, Gregersen BA, Klepeis JL, Kolossváry I, Shan Y, Shaw DE. Arkin IT, et al. Among authors: shaw de. Science. 2007 Aug 10;317(5839):799-803. doi: 10.1126/science.1142824. Science. 2007. PMID: 17690293
A conserved protonation-dependent switch controls drug binding in the Abl kinase.
Shan Y, Seeliger MA, Eastwood MP, Frank F, Xu H, Jensen MØ, Dror RO, Kuriyan J, Shaw DE. Shan Y, et al. Among authors: shaw de. Proc Natl Acad Sci U S A. 2009 Jan 6;106(1):139-44. doi: 10.1073/pnas.0811223106. Epub 2008 Dec 24. Proc Natl Acad Sci U S A. 2009. PMID: 19109437 Free PMC article.
Principles of conduction and hydrophobic gating in K+ channels.
Jensen MØ, Borhani DW, Lindorff-Larsen K, Maragakis P, Jogini V, Eastwood MP, Dror RO, Shaw DE. Jensen MØ, et al. Among authors: shaw de. Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):5833-8. doi: 10.1073/pnas.0911691107. Epub 2010 Mar 15. Proc Natl Acad Sci U S A. 2010. PMID: 20231479 Free PMC article.
Structure and function of an irreversible agonist-β(2) adrenoceptor complex.
Rosenbaum DM, Zhang C, Lyons JA, Holl R, Aragao D, Arlow DH, Rasmussen SG, Choi HJ, Devree BT, Sunahara RK, Chae PS, Gellman SH, Dror RO, Shaw DE, Weis WI, Caffrey M, Gmeiner P, Kobilka BK. Rosenbaum DM, et al. Among authors: shaw de. Nature. 2011 Jan 13;469(7329):236-40. doi: 10.1038/nature09665. Nature. 2011. PMID: 21228876 Free PMC article.
267 results