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How autoreactive thymocytes differentiate into regulatory versus effector CD4+ T cells after avoiding clonal deletion.
Tai X, Indart A, Rojano M, Guo J, Apenes N, Kadakia T, Craveiro M, Alag A, Etzensperger R, Badr ME, Zhang F, Zhang Z, Mu J, Guinter T, Crossman A, Granger L, Sharrow S, Zhou X, Singer A. Tai X, et al. Among authors: sharrow s. Nat Immunol. 2023 Apr;24(4):637-651. doi: 10.1038/s41590-023-01469-2. Epub 2023 Mar 23. Nat Immunol. 2023. PMID: 36959291 Free PMC article.
DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier.
Santos MA, Faryabi RB, Ergen AV, Day AM, Malhowski A, Canela A, Onozawa M, Lee JE, Callen E, Gutierrez-Martinez P, Chen HT, Wong N, Finkel N, Deshpande A, Sharrow S, Rossi DJ, Ito K, Ge K, Aplan PD, Armstrong SA, Nussenzweig A. Santos MA, et al. Among authors: sharrow s. Nature. 2014 Oct 2;514(7520):107-11. doi: 10.1038/nature13483. Epub 2014 Jul 27. Nature. 2014. PMID: 25079327 Free PMC article.
Thymic medullary epithelium and thymocyte self-tolerance require cooperation between CD28-CD80/86 and CD40-CD40L costimulatory pathways.
Williams JA, Zhang J, Jeon H, Nitta T, Ohigashi I, Klug D, Kruhlak MJ, Choudhury B, Sharrow SO, Granger L, Adams A, Eckhaus MA, Jenkinson SR, Richie ER, Gress RE, Takahama Y, Hodes RJ. Williams JA, et al. Among authors: sharrow so. J Immunol. 2014 Jan 15;192(2):630-40. doi: 10.4049/jimmunol.1302550. Epub 2013 Dec 13. J Immunol. 2014. PMID: 24337745 Free PMC article.
TRAF3 enforces the requirement for T cell cross-talk in thymic medullary epithelial development.
Jenkinson SR, Williams JA, Jeon H, Zhang J, Nitta T, Ohigashi I, Kruhlak M, Zuklys S, Sharrow S, Adams A, Granger L, Choi Y, Siebenlist U, Bishop GA, Hollander GA, Takahama Y, Hodes RJ. Jenkinson SR, et al. Among authors: sharrow s. Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21107-12. doi: 10.1073/pnas.1314859111. Epub 2013 Dec 9. Proc Natl Acad Sci U S A. 2013. PMID: 24324158 Free PMC article.
Basis of CTLA-4 function in regulatory and conventional CD4(+) T cells.
Tai X, Van Laethem F, Pobezinsky L, Guinter T, Sharrow SO, Adams A, Granger L, Kruhlak M, Lindsten T, Thompson CB, Feigenbaum L, Singer A. Tai X, et al. Among authors: sharrow so. Blood. 2012 May 31;119(22):5155-63. doi: 10.1182/blood-2011-11-388918. Epub 2012 Mar 7. Blood. 2012. PMID: 22403258 Free PMC article.
176 results