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Argonaute Utilization for miRNA Silencing Is Determined by Phosphorylation-Dependent Recruitment of LIM-Domain-Containing Proteins.
Bridge KS, Shah KM, Li Y, Foxler DE, Wong SCK, Miller DC, Davidson KM, Foster JG, Rose R, Hodgkinson MR, Ribeiro PS, Aboobaker AA, Yashiro K, Wang X, Graves PR, Plevin MJ, Lagos D, Sharp TV. Bridge KS, et al. Among authors: sharp tv. Cell Rep. 2017 Jul 5;20(1):173-187. doi: 10.1016/j.celrep.2017.06.027. Cell Rep. 2017. PMID: 28683311 Free PMC article.
A HIF-LIMD1 negative feedback mechanism mitigates the pro-tumorigenic effects of hypoxia.
Foxler DE, Bridge KS, Foster JG, Grevitt P, Curry S, Shah KM, Davidson KM, Nagano A, Gadaleta E, Rhys HI, Kennedy PT, Hermida MA, Chang TY, Shaw PE, Reynolds LE, McKay TR, Wang HW, Ribeiro PS, Plevin MJ, Lagos D, Lemoine NR, Rajan P, Graham TA, Chelala C, Hodivala-Dilke KM, Spendlove I, Sharp TV. Foxler DE, et al. Among authors: sharp tv. EMBO Mol Med. 2018 Aug;10(8):e8304. doi: 10.15252/emmm.201708304. EMBO Mol Med. 2018. PMID: 29930174 Free PMC article.
Targeted therapy for LIMD1-deficient non-small cell lung cancer subtypes.
Davidson K, Grevitt P, Contreras-Gerenas MF, Bridge KS, Hermida M, Shah KM, Mardakheh FK, Stubbs M, Burke R, Casado P, Cutillas PR, Martin SA, Sharp TV. Davidson K, et al. Among authors: sharp tv. Cell Death Dis. 2021 Nov 11;12(11):1075. doi: 10.1038/s41419-021-04355-7. Cell Death Dis. 2021. PMID: 34764236 Free PMC article.
CSN1 Somatic Mutations in Penile Squamous Cell Carcinoma.
Feber A, Worth DC, Chakravarthy A, de Winter P, Shah K, Arya M, Saqib M, Nigam R, Malone PR, Tan WS, Rodney S, Freeman A, Jameson C, Wilson GA, Powles T, Beck S, Fenton T, Sharp TV, Muneer A, Kelly JD. Feber A, et al. Among authors: sharp tv. Cancer Res. 2016 Aug 15;76(16):4720-4727. doi: 10.1158/0008-5472.CAN-15-3134. Epub 2016 Jun 20. Cancer Res. 2016. PMID: 27325650 Free PMC article.
LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing.
James V, Zhang Y, Foxler DE, de Moor CH, Kong YW, Webb TM, Self TJ, Feng Y, Lagos D, Chu CY, Rana TM, Morley SJ, Longmore GD, Bushell M, Sharp TV. James V, et al. Among authors: sharp tv. Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12499-504. doi: 10.1073/pnas.0914987107. Epub 2010 Jun 28. Proc Natl Acad Sci U S A. 2010. PMID: 20616046 Free PMC article.
47 results