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A phase I trial of radioimmunotherapy with 131I-A5B7 anti-CEA antibody in combination with combretastatin-A4-phosphate in advanced gastrointestinal carcinomas.
Meyer T, Gaya AM, Dancey G, Stratford MR, Othman S, Sharma SK, Wellsted D, Taylor NJ, Stirling JJ, Poupard L, Folkes LK, Chan PS, Pedley RB, Chester KA, Owen K, Violet JA, Malaroda A, Green AJ, Buscombe J, Padhani AR, Rustin GJ, Begent RH. Meyer T, et al. Among authors: sharma sk. Clin Cancer Res. 2009 Jul 1;15(13):4484-92. doi: 10.1158/1078-0432.CCR-09-0035. Epub 2009 Jun 23. Clin Cancer Res. 2009. PMID: 19549771 Free article. Clinical Trial.
Recombinant anti-carcinoembryonic antigen antibodies for targeting cancer.
Chester KA, Mayer A, Bhatia J, Robson L, Spencer DI, Cooke SP, Flynn AA, Sharma SK, Boxer G, Pedley RB, Begent RH. Chester KA, et al. Among authors: sharma sk. Cancer Chemother Pharmacol. 2000;46 Suppl:S8-12. doi: 10.1007/pl00014055. Cancer Chemother Pharmacol. 2000. PMID: 10950140 Review.
Antibody-directed enzyme-prodrug therapy.
Pedley RB, Sharma SK, Hawkins RE, Chester KA. Pedley RB, et al. Methods Mol Med. 2004;90:491-514. doi: 10.1385/1-59259-429-8:491. Methods Mol Med. 2004. PMID: 14657581 No abstract available.
Radiolabelling of glycosylated MFE-23::CPG2 fusion protein (MFECP1) with 99mTc for quantitation of tumour antibody-enzyme localisation in antibody-directed enzyme pro-drug therapy (ADEPT).
Francis RJ, Mather SJ, Chester K, Sharma SK, Bhatia J, Pedley RB, Waibel R, Green AJ, Begent RH. Francis RJ, et al. Among authors: sharma sk. Eur J Nucl Med Mol Imaging. 2004 Aug;31(8):1090-6. doi: 10.1007/s00259-004-1474-4. Epub 2004 Mar 17. Eur J Nucl Med Mol Imaging. 2004. PMID: 15029458
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