Sharma RK - Search Results

1

Design, Syntheses, and Bioevaluations of Some Novel N²-Acryloylbenzohydrazides as Chemostimulants and Cytotoxic Agents.

Lakhani K, Borrego EA, Cano KG, Dimmock JR, Aguilera RJ, Das S, Roayapalley PK, Sharma RK, Das U. Lakhani K, et al. Among authors: sharma rk. Medicines (Basel). 2021 Jun 3;8(6):27. doi: 10.3390/medicines8060027. Medicines (Basel). 2021. PMID: 34205029 Free PMC article.

2

Design, Synthesis and Tumour-Selective Toxicity of Novel 1-[3-{3,5-Bis(benzylidene)-4-oxo-1-piperidino}-3-oxopropyl]-4-piperidone Oximes and Related Quaternary Ammonium Salts.

Roayapalley PK, Dimmock JR, Contreras L, Balderrama KS, Aguilera RJ, Sakagami H, Amano S, Sharma RK, Das U. Roayapalley PK, et al. Among authors: sharma rk. Molecules. 2021 Nov 25;26(23):7132. doi: 10.3390/molecules26237132. Molecules. 2021. PMID: 34885719 Free PMC article.

3

Cytotoxic Tumour-Selective 1,5-Diaryl-3-Oxo-1,4-Pentadienes Mounted on a Piperidine Ring.

Roayapalley PK, Sakagami H, Satoh K, Amano S, Bandow K, Aguilera RJ, Hernandez KGC, Schiaffino Bustamante AY, Dimmock SG, Sharma RK, Das U, Dimmock JR. Roayapalley PK, et al. Among authors: sharma rk. Medicines (Basel). 2021 Dec 16;8(12):78. doi: 10.3390/medicines8120078. Medicines (Basel). 2021. PMID: 34940290 Free PMC article.

4

Design, synthesis and cytotoxic properties of novel 1-[4-(2-alkylaminoethoxy)phenylcarbonyl]-3,5-bis(arylidene)-4-piperidones and related compounds.

Das U, Alcorn J, Shrivastav A, Sharma RK, De Clercq E, Balzarini J, Dimmock JR. Das U, et al. Among authors: sharma rk. Eur J Med Chem. 2007 Jan;42(1):71-80. doi: 10.1016/j.ejmech.2006.08.002. Epub 2006 Sep 22. Eur J Med Chem. 2007. PMID: 16996657

5

Cytotoxic thiol alkylators.

Pati HN, Das U, Sharma RK, Dimmock JR. Pati HN, et al. Among authors: sharma rk. Mini Rev Med Chem. 2007 Feb;7(2):131-9. doi: 10.2174/138955707779802642. Mini Rev Med Chem. 2007. PMID: 17305587 Review.

6

N-acyl-3,5-bis(arylidene)-4-piperidones and related compounds which stimulate fyn kinase.

Das U, Selvakumar P, Sharma RK, Haas TA, Dimmock JR. Das U, et al. Among authors: sharma rk. J Enzyme Inhib Med Chem. 2007 Aug;22(4):451-5. doi: 10.1080/14756360701192515. J Enzyme Inhib Med Chem. 2007. PMID: 17847712

7

1-[4-(2-Dimethylaminoethoxy)phenylcarbonyl]-3,5-Bis(3,4,5-Trimethoxybenzylidene)- 4-Piperidone Hydrochloride and Related Compounds: Potent Cytotoxins Demonstrate Greater Toxicity to Neoplasms than Non- Malignant Cells.

Roayapalley PK, Dimmock JR, Sakagami H, Okudaira N, Sharma RK, Das U. Roayapalley PK, et al. Among authors: sharma rk. Med Chem. 2022;18(9):1001-1012. doi: 10.2174/1573406418666220322154110. Med Chem. 2022. PMID: 35319387

8

NC2213: a novel methionine aminopeptidase 2 inhibitor in human colon cancer HT29 cells.

Selvakumar P, Lakshmikuttyamma A, Das U, Pati HN, Dimmock JR, Sharma RK. Selvakumar P, et al. Among authors: sharma rk. Mol Cancer. 2009 Aug 24;8:65. doi: 10.1186/1476-4598-8-65. Mol Cancer. 2009. PMID: 19703310 Free PMC article.

9

3,5-Bis(benzylidene)-4-oxo-1-phosphonopiperidines and related diethyl esters: Potent cytotoxins with multi-drug-resistance reverting properties.

Das S, Das U, Selvakumar P, Sharma RK, Balzarini J, De Clercq E, Molnár J, Serly J, Baráth Z, Schatte G, Bandy B, Gorecki DK, Dimmock JR. Das S, et al. Among authors: sharma rk. ChemMedChem. 2009 Nov;4(11):1831-40. doi: 10.1002/cmdc.200900288. ChemMedChem. 2009. PMID: 19802855 Free PMC article.

10

3,5-Bis(benzylidene)-1-[4-2-(morpholin-4-yl)ethoxyphenylcarbonyl]-4-piperidone hydrochloride: a lead tumor-specific cytotoxin which induces apoptosis and autophagy.

Das U, Sakagami H, Chu Q, Wang Q, Kawase M, Selvakumar P, Sharma RK, Dimmock JR. Das U, et al. Among authors: sharma rk. Bioorg Med Chem Lett. 2010 Feb 1;20(3):912-7. doi: 10.1016/j.bmcl.2009.12.076. Epub 2009 Dec 24. Bioorg Med Chem Lett. 2010. PMID: 20064715 Free PMC article.

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