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Cytotoxic thiol alkylators.
Pati HN, Das U, Sharma RK, Dimmock JR. Pati HN, et al. Among authors: sharma rk. Mini Rev Med Chem. 2007 Feb;7(2):131-9. doi: 10.2174/138955707779802642. Mini Rev Med Chem. 2007. PMID: 17305587 Review.
Cytotoxic 1,4-bis(2-oxo-1-cycloalkylmethylene)benzenes and related compounds.
Dimmock JR, Jha A, Kumar P, Zello GA, Quail JW, Oloo EO, Oucharek JJ, Pasha MK, Seitz D, Sharma RK, Allen TM, Santos CL, Manavathu EK, De Clercq E, Balzarini J, Stables JP. Dimmock JR, et al. Among authors: sharma rk. Eur J Med Chem. 2002 Jan;37(1):35-44. doi: 10.1016/s0223-5234(01)01294-6. Eur J Med Chem. 2002. PMID: 11841873
Cytotoxic 5-aryl-1-(4-nitrophenyl)-3-oxo-1,4-pentadienes mounted on alicyclic scaffolds.
Das U, Gul HI, Alcorn J, Shrivastav A, George T, Sharma RK, Nienaber KH, De Clercq E, Balzarini J, Kawase M, Kan N, Tanaka T, Tani S, Werbovetz KA, Yakovich AJ, Manavathu EK, Stables JP, Dimmock JR. Das U, et al. Among authors: sharma rk. Eur J Med Chem. 2006 May;41(5):577-85. doi: 10.1016/j.ejmech.2005.12.014. Epub 2006 Apr 3. Eur J Med Chem. 2006. PMID: 16581158
Derivatives of aryl amines containing the cytotoxic 1,4-dioxo-2-butenyl pharmacophore.
Jha A, Mukherjee C, Prasad AK, Parmar VS, Vadaparti M, Das U, De Clercq E, Balzarini J, Stables JP, Shrivastav A, Sharma RK, Dimmock JR. Jha A, et al. Among authors: sharma rk. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1510-5. doi: 10.1016/j.bmcl.2010.01.098. Epub 2010 Jan 25. Bioorg Med Chem Lett. 2010. PMID: 20149656 Free PMC article.
2,340 results