Sharma N - Search Results

1

The emerging paradigm of calcium homeostasis as a new therapeutic target for protozoan parasites.

Gupta Y, Goicoechea S, Pearce CM, Mathur R, Romero JG, Kwofie SK, Weyenberg MC, Daravath B, Sharma N, Poonam, Akala HM, Kanzok SM, Durvasula R, Rathi B, Kempaiah P. Gupta Y, et al. Among authors: sharma n. Med Res Rev. 2022 Jan;42(1):56-82. doi: 10.1002/med.21804. Epub 2021 Apr 13. Med Res Rev. 2022. PMID: 33851452 Review.

2

Small Molecules Effective Against Liver and Blood Stage Malarial Infection.

Singh S, Sharma N, Upadhyay C, Kumar S, Rathi B, Poonam. Singh S, et al. Among authors: sharma n. Curr Top Med Chem. 2019;18(23):2008-2021. doi: 10.2174/1568026619666181129143623. Curr Top Med Chem. 2019. PMID: 30499395 Review.

3

Novel Antiplasmodial Compounds Leveraged with Multistage Potency against the Parasite Plasmodium falciparum: In Vitro and In Vivo Evaluations and Pharmacokinetic Studies.

Sharma N, Kashif M, Singh V, Fontinha D, Mukherjee B, Kumar D, Singh S, Prudencio M, Singh AP, Rathi B. Sharma N, et al. J Med Chem. 2021 Jun 24;64(12):8666-8683. doi: 10.1021/acs.jmedchem.1c00659. Epub 2021 Jun 14. J Med Chem. 2021. PMID: 34124905

4

Antiviral evaluation of hydroxyethylamine analogs: Inhibitors of SARS-CoV-2 main protease (3CLpro), a virtual screening and simulation approach.

Gupta Y, Kumar S, Zak SE, Jones KA, Upadhyay C, Sharma N, Azizi SA, Kathayat RS, Poonam, Herbert AS, Durvasula R, Dickinson BC, Dye JM, Rathi B, Kempaiah P. Gupta Y, et al. Among authors: sharma n. Bioorg Med Chem. 2021 Oct 1;47:116393. doi: 10.1016/j.bmc.2021.116393. Epub 2021 Sep 4. Bioorg Med Chem. 2021. PMID: 34509862 Free PMC article.

5

A novel compound active against SARS-CoV-2 targeting uridylate-specific endoribonuclease (NendoU/NSP15): in silico and in vitro investigations.

Kumar S, Gupta Y, Zak SE, Upadhyay C, Sharma N, Herbert AS, Durvasula R, Potemkin V, Dye JM, Poonam, Kempaiah P, Rathi B. Kumar S, et al. Among authors: sharma n. RSC Med Chem. 2021 Aug 18;12(10):1757-1764. doi: 10.1039/d1md00202c. eCollection 2021 Oct 20. RSC Med Chem. 2021. PMID: 34778776 Free PMC article.

6

Theoretical and experimental studies of an oseltamivir-triazole-based thermoresponsive organogel.

Kumar S, Wu L, Sharma N, Ayushee, Kaushik K, Grishina M, Chhikara BS, Poonam, Potemkin V, Rathi B. Kumar S, et al. Among authors: sharma n. RSC Adv. 2019 Jul 4;9(36):21031-21041. doi: 10.1039/c9ra02463h. eCollection 2019 Jul 1. RSC Adv. 2019. PMID: 35515532 Free PMC article.

7

Multistage antiplasmodial activity of hydroxyethylamine compounds, in vitro and in vivo evaluations.

Sharma N, Gupta Y, Bansal M, Singh S, Pathak P, Shahbaaz M, Mathur R, Singh J, Kashif M, Grishina M, Potemkin V, Rajendran V, Poonam, Kempaiah P, Singh AP, Rathi B. Sharma N, et al. RSC Adv. 2020 Sep 25;10(58):35516-35530. doi: 10.1039/d0ra03997g. eCollection 2020 Sep 21. RSC Adv. 2020. PMID: 35686031 Free PMC article.

8

Designing and development of phthalimides as potent anti-tubulin hybrid molecules against malaria.

Singh V, Hada RS, Jain R, Vashistha M, Kumari G, Singh S, Sharma N, Bansal M, Poonam, Zoltner M, Caffrey CR, Rathi B, Singh S. Singh V, et al. Among authors: sharma n. Eur J Med Chem. 2022 Sep 5;239:114534. doi: 10.1016/j.ejmech.2022.114534. Epub 2022 Jun 15. Eur J Med Chem. 2022. PMID: 35749989

9

The Multistage Antimalarial Compound Calxinin Perturbates P. falciparum Ca²⁺ Homeostasis by Targeting a Unique Ion Channel.

Gupta Y, Sharma N, Singh S, Romero JG, Rajendran V, Mogire RM, Kashif M, Beach J, Jeske W, Poonam, Ogutu BR, Kanzok SM, Akala HM, Legac J, Rosenthal PJ, Rademacher DJ, Durvasula R, Singh AP, Rathi B, Kempaiah P. Gupta Y, et al. Among authors: sharma n. Pharmaceutics. 2022 Jun 28;14(7):1371. doi: 10.3390/pharmaceutics14071371. Pharmaceutics. 2022. PMID: 35890267 Free PMC article.

10

Solvent-free mechanochemical grinding facilitates clean synthesis of N-substituted amines.

Sharma N, Sharma H, Kumar M, Grishina M, Pandit U, Poonam, Rathi B. Sharma N, et al. Among authors: sharma h. Org Biomol Chem. 2022 Aug 24;20(33):6673-6679. doi: 10.1039/d2ob01148d. Org Biomol Chem. 2022. PMID: 35947022

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