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Schweinfurthin natural products induce regression of murine melanoma and pair with anti-PD-1 therapy to facilitate durable tumor immunity.
Kokolus KM, Haley JS, Koubek EJ, Gowda R, Dinavahi SS, Sharma A, Claxton DF, Helm KF, Drabick JJ, Robertson GP, Neighbors JD, Hohl RJ, Schell TD. Kokolus KM, et al. Among authors: sharma a. Oncoimmunology. 2018 Nov 11;8(2):e1539614. doi: 10.1080/2162402X.2018.1539614. eCollection 2019. Oncoimmunology. 2018. PMID: 30713799 Free PMC article.
The novel Isatin analog KS99 targets stemness markers in acute myeloid leukemia.
Annageldiyev C, Gowda K, Patel T, Bhattacharya P, Tan SF, Iyer S, Desai D, Dovat S, Feith DJ, Loughran TP Jr, Amin S, Claxton D, Sharma A. Annageldiyev C, et al. Among authors: sharma a. Haematologica. 2020 Mar;105(3):687-696. doi: 10.3324/haematol.2018.212886. Epub 2019 May 23. Haematologica. 2020. PMID: 31123028 Free PMC article.
The PI3K/AKT Pathway Inhibitor ISC-4 Induces Apoptosis and Inhibits Growth of Leukemia in Preclinical Models of Acute Myeloid Leukemia.
Annageldiyev C, Tan SF, Thakur S, Dhanyamraju PK, Ramisetti SR, Bhadauria P, Schick J, Zeng Z, Sharma V, Dunton W, Dovat S, Desai D, Zheng H, Feith DJ, Loughran TP Jr, Amin S, Sharma AK, Claxton D, Sharma A. Annageldiyev C, et al. Among authors: sharma a, sharma ak, sharma v. Front Oncol. 2020 Apr 1;10:393. doi: 10.3389/fonc.2020.00393. eCollection 2020. Front Oncol. 2020. PMID: 32296637 Free PMC article.
Dual targeting of MTOR as a novel therapeutic approach for high-risk B-cell acute lymphoblastic leukemia.
Ge Z, Song C, Ding Y, Tan BH, Desai D, Sharma A, Gowda R, Yue F, Huang S, Spiegelman V, Payne JL, Reeves ME, Iyer S, Dhanyamraju PK, Imamura Y, Bogush D, Bamme Y, Yang Y, Soliman M, Kane S, Dovat E, Schramm J, Hu T, McGrath M, Chroneos ZC, Payne KJ, Gowda C, Dovat S. Ge Z, et al. Among authors: sharma a. Leukemia. 2021 May;35(5):1267-1278. doi: 10.1038/s41375-021-01132-5. Epub 2021 Feb 2. Leukemia. 2021. PMID: 33531656 Free PMC article.
DJ4 Targets the Rho-Associated Protein Kinase Pathway and Attenuates Disease Progression in Preclinical Murine Models of Acute Myeloid Leukemia.
Golla U, Ehudin MA, Annageldiyev C, Zeng Z, Bastihalli Tukaramrao D, Tarren A, Date AA, Elcheva I, Berg A, Amin S, Loughran TP Jr, Kester M, Desai D, Dovat S, Claxton D, Sharma A. Golla U, et al. Among authors: sharma a. Cancers (Basel). 2021 Sep 29;13(19):4889. doi: 10.3390/cancers13194889. Cancers (Basel). 2021. PMID: 34638385 Free PMC article.
Therapeutic Benefits of Selenium in Hematological Malignancies.
Ehudin MA, Golla U, Trivedi D, Potlakayala SD, Rudrabhatla SV, Desai D, Dovat S, Claxton D, Sharma A. Ehudin MA, et al. Among authors: sharma a. Int J Mol Sci. 2022 Jul 19;23(14):7972. doi: 10.3390/ijms23147972. Int J Mol Sci. 2022. PMID: 35887320 Free PMC article. Review.
Signaling pathways and regulation of gene expression in hematopoietic cells.
Bogush D, Schramm J, Ding Y, He B, Singh C, Sharma A, Tukaramrao DB, Iyer S, Desai D, Nalesnik G, Hengst J, Bhalodia R, Gowda C, Dovat S. Bogush D, et al. Among authors: sharma a. Adv Biol Regul. 2023 May;88:100942. doi: 10.1016/j.jbior.2022.100942. Epub 2022 Dec 15. Adv Biol Regul. 2023. PMID: 36621151 Review.
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