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5-methylcytosine (m5C) RNA modification controls the innate immune response to virus infection by regulating type I interferons.
Zhang Y, Zhang LS, Dai Q, Chen P, Lu M, Kairis EL, Murugaiah V, Xu J, Shukla RK, Liang X, Zou Z, Cormet-Boyaka E, Qiu J, Peeples ME, Sharma A, He C, Li J. Zhang Y, et al. Among authors: sharma a. Proc Natl Acad Sci U S A. 2022 Oct 18;119(42):e2123338119. doi: 10.1073/pnas.2123338119. Epub 2022 Oct 14. Proc Natl Acad Sci U S A. 2022. PMID: 36240321 Free PMC article.
Butyrate Reprograms Expression of Specific Interferon-Stimulated Genes.
Chemudupati M, Kenney AD, Smith AC, Fillinger RJ, Zhang L, Zani A, Liu SL, Anderson MZ, Sharma A, Yount JS. Chemudupati M, et al. Among authors: sharma a. J Virol. 2020 Jul 30;94(16):e00326-20. doi: 10.1128/JVI.00326-20. Print 2020 Jul 30. J Virol. 2020. PMID: 32461320 Free PMC article.
Rationally Designed ACE2-Derived Peptides Inhibit SARS-CoV-2.
Larue RC, Xing E, Kenney AD, Zhang Y, Tuazon JA, Li J, Yount JS, Li PK, Sharma A. Larue RC, et al. Among authors: sharma a. Bioconjug Chem. 2021 Jan 20;32(1):215-223. doi: 10.1021/acs.bioconjchem.0c00664. Epub 2020 Dec 24. Bioconjug Chem. 2021. PMID: 33356169 Free PMC article.
Viral RNA N6-methyladenosine modification modulates both innate and adaptive immune responses of human respiratory syncytial virus.
Xue M, Zhang Y, Wang H, Kairis EL, Lu M, Ahmad S, Attia Z, Harder O, Zhang Z, Wei J, Chen P, Gao Y, Peeples ME, Sharma A, Boyaka P, He C, Hur S, Niewiesk S, Li J. Xue M, et al. Among authors: sharma a. PLoS Pathog. 2021 Dec 20;17(12):e1010142. doi: 10.1371/journal.ppat.1010142. eCollection 2021 Dec. PLoS Pathog. 2021. PMID: 34929018 Free PMC article.
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