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The multiplex network of human diseases.
Halu A, De Domenico M, Arenas A, Sharma A. Halu A, et al. Among authors: sharma a. NPJ Syst Biol Appl. 2019 Apr 23;5:15. doi: 10.1038/s41540-019-0092-5. eCollection 2019. NPJ Syst Biol Appl. 2019. PMID: 31044086 Free PMC article.
Human symptoms-disease network.
Zhou X, Menche J, Barabási AL, Sharma A. Zhou X, et al. Among authors: sharma a. Nat Commun. 2014 Jun 26;5:4212. doi: 10.1038/ncomms5212. Nat Commun. 2014. PMID: 24967666 Free article.
Endophenotype Network Models: Common Core of Complex Diseases.
Ghiassian SD, Menche J, Chasman DI, Giulianini F, Wang R, Ricchiuto P, Aikawa M, Iwata H, Müller C, Zeller T, Sharma A, Wild P, Lackner K, Singh S, Ridker PM, Blankenberg S, Barabási AL, Loscalzo J. Ghiassian SD, et al. Among authors: sharma a. Sci Rep. 2016 Jun 9;6:27414. doi: 10.1038/srep27414. Sci Rep. 2016. PMID: 27278246 Free PMC article.
PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation.
Iwata H, Goettsch C, Sharma A, Ricchiuto P, Goh WW, Halu A, Yamada I, Yoshida H, Hara T, Wei M, Inoue N, Fukuda D, Mojcher A, Mattson PC, Barabási AL, Boothby M, Aikawa E, Singh SA, Aikawa M. Iwata H, et al. Among authors: sharma a. Nat Commun. 2016 Oct 31;7:12849. doi: 10.1038/ncomms12849. Nat Commun. 2016. PMID: 27796300 Free PMC article.
Spatiotemporal Multi-Omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease.
Schlotter F, Halu A, Goto S, Blaser MC, Body SC, Lee LH, Higashi H, DeLaughter DM, Hutcheson JD, Vyas P, Pham T, Rogers MA, Sharma A, Seidman CE, Loscalzo J, Seidman JG, Aikawa M, Singh SA, Aikawa E. Schlotter F, et al. Among authors: sharma a. Circulation. 2018 Jul 24;138(4):377-393. doi: 10.1161/CIRCULATIONAHA.117.032291. Circulation. 2018. PMID: 29588317 Free PMC article.
Controllability in an islet specific regulatory network identifies the transcriptional factor NFATC4, which regulates Type 2 Diabetes associated genes.
Sharma A, Halu A, Decano JL, Padi M, Liu YY, Prasad RB, Fadista J, Santolini M, Menche J, Weiss ST, Vidal M, Silverman EK, Aikawa M, Barabási AL, Groop L, Loscalzo J. Sharma A, et al. NPJ Syst Biol Appl. 2018 Jul 3;4:25. doi: 10.1038/s41540-018-0057-0. eCollection 2018. NPJ Syst Biol Appl. 2018. PMID: 29977601 Free PMC article.
Uremic Toxin Indoxyl Sulfate Promotes Proinflammatory Macrophage Activation Via the Interplay of OATP2B1 and Dll4-Notch Signaling.
Nakano T, Katsuki S, Chen M, Decano JL, Halu A, Lee LH, Pestana DVS, Kum AST, Kuromoto RK, Golden WS, Boff MS, Guimaraes GC, Higashi H, Kauffman KJ, Maejima T, Suzuki T, Iwata H, Barabási AL, Aster JC, Anderson DG, Sharma A, Singh SA, Aikawa E, Aikawa M. Nakano T, et al. Among authors: sharma a. Circulation. 2019 Jan 2;139(1):78-96. doi: 10.1161/CIRCULATIONAHA.118.034588. Circulation. 2019. PMID: 30586693 Free PMC article.
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