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MEK activation modulates glycolysis and supports suppressive myeloid cells in TNBC.
Franklin DA, Sharick JT, Ericsson-Gonzalez PI, Sanchez V, Dean PT, Opalenik SR, Cairo S, Judde JG, Lewis MT, Chang JC, Sanders ME, Cook RS, Skala MC, Bordeaux J, Orozco Bender J, Vaupel C, Geiss G, Hinerfeld D, Balko JM. Franklin DA, et al. Among authors: sharick jt. JCI Insight. 2020 Aug 6;5(15):e134290. doi: 10.1172/jci.insight.134290. JCI Insight. 2020. PMID: 32634121 Free PMC article.
Imaging intratumoral metabolic heterogeneity.
Walsh AJ, Sharick JT, Skala MC. Walsh AJ, et al. Among authors: sharick jt. Nat Biomed Eng. 2019 May;3(5):333-334. doi: 10.1038/s41551-019-0398-z. Nat Biomed Eng. 2019. PMID: 31073174 No abstract available.
Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models.
Schulte ML, Fu A, Zhao P, Li J, Geng L, Smith ST, Kondo J, Coffey RJ, Johnson MO, Rathmell JC, Sharick JT, Skala MC, Smith JA, Berlin J, Washington MK, Nickels ML, Manning HC. Schulte ML, et al. Among authors: sharick jt. Nat Med. 2018 Feb;24(2):194-202. doi: 10.1038/nm.4464. Epub 2018 Jan 15. Nat Med. 2018. PMID: 29334372 Free PMC article.
Patient-Derived Cancer Organoid Cultures to Predict Sensitivity to Chemotherapy and Radiation.
Pasch CA, Favreau PF, Yueh AE, Babiarz CP, Gillette AA, Sharick JT, Karim MR, Nickel KP, DeZeeuw AK, Sprackling CM, Emmerich PB, DeStefanis RA, Pitera RT, Payne SN, Korkos DP, Clipson L, Walsh CM, Miller D, Carchman EH, Burkard ME, Lemmon KK, Matkowskyj KA, Newton MA, Ong IM, Bassetti MF, Kimple RJ, Skala MC, Deming DA. Pasch CA, et al. Among authors: sharick jt. Clin Cancer Res. 2019 Sep 1;25(17):5376-5387. doi: 10.1158/1078-0432.CCR-18-3590. Epub 2019 Jun 7. Clin Cancer Res. 2019. PMID: 31175091 Free PMC article.
16 results