Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

96 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Mismatch repair protein MLH1 suppresses replicative stress in BRCA2-deficient breast tumors.
Sengodan SK, Hu X, Peddibhotla V, Balamurugan K, Mitrophanov AY, McKennett L, Kharat SS, Sanawar R, Singh VK, Albaugh ME, Burkett SS, Zhao Y, Tran B, Malys T, Sterneck E, De S, Sharan SK. Sengodan SK, et al. Among authors: sharan sk. J Clin Invest. 2024 Jan 25;134(7):e173718. doi: 10.1172/JCI173718. J Clin Invest. 2024. PMID: 38271119 Free PMC article.
Degradation of 5hmC-marked stalled replication forks by APE1 causes genomic instability.
Kharat SS, Ding X, Swaminathan D, Suresh A, Singh M, Sengodan SK, Burkett S, Marks H, Pamala C, He Y, Fox SD, Buehler EC, Muegge K, Martin SE, Sharan SK. Kharat SS, et al. Among authors: sharan sk. Sci Signal. 2020 Aug 18;13(645):eaba8091. doi: 10.1126/scisignal.aba8091. Sci Signal. 2020. PMID: 32817374 Free PMC article.
Saturation genome editing of 11 codons and exon 13 of BRCA2 coupled with chemotherapeutic drug response accurately determines pathogenicity of variants.
Sahu S, Sullivan TL, Mitrophanov AY, Galloux M, Nousome D, Southon E, Caylor D, Mishra AP, Evans CN, Clapp ME, Burkett S, Malys T, Chari R, Biswas K, Sharan SK. Sahu S, et al. Among authors: sharan sk. PLoS Genet. 2023 Sep 15;19(9):e1010940. doi: 10.1371/journal.pgen.1010940. eCollection 2023 Sep. PLoS Genet. 2023. PMID: 37713444 Free PMC article.
Characterization of BRCA2 R3052Q variant in mice supports its functional impact as a low-risk variant.
Mishra AP, Hartford S, Chittela RK, Sahu S, Kharat SS, Alvaro-Aranda L, Contreras-Perez A, Sullivan T, Martin BK, Albaugh M, Southon E, Burkett S, Karim B, Carreira A, Tessarollo L, Sharan SK. Mishra AP, et al. Among authors: sharan sk. Cell Death Dis. 2023 Nov 18;14(11):753. doi: 10.1038/s41419-023-06289-8. Cell Death Dis. 2023. PMID: 37980415 Free PMC article.
Sequencing-based functional assays for classification of BRCA2 variants in mouse ESCs.
Biswas K, Mitrophanov AY, Sahu S, Sullivan T, Southon E, Nousome D, Reid S, Narula S, Smolen J, Sengupta T, Riedel-Topper M, Kapoor M, Babbar A, Stauffer S, Cleveland L, Tandon M, Malys T, Sharan SK. Biswas K, et al. Among authors: sharan sk. Cell Rep Methods. 2023 Nov 20;3(11):100628. doi: 10.1016/j.crmeth.2023.100628. Epub 2023 Nov 2. Cell Rep Methods. 2023. PMID: 37922907 Free PMC article.
Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2.
Hartford SA, Chittela R, Ding X, Vyas A, Martin B, Burkett S, Haines DC, Southon E, Tessarollo L, Sharan SK. Hartford SA, et al. Among authors: sharan sk. PLoS Genet. 2016 Aug 4;12(8):e1006236. doi: 10.1371/journal.pgen.1006236. eCollection 2016 Aug. PLoS Genet. 2016. PMID: 27490902 Free PMC article.
BRCA2-DSS1 interaction is dispensable for RAD51 recruitment at replication-induced and meiotic DNA double strand breaks.
Mishra AP, Hartford SA, Sahu S, Klarmann K, Chittela RK, Biswas K, Jeon AB, Martin BK, Burkett S, Southon E, Reid S, Albaugh ME, Karim B, Tessarollo L, Keller JR, Sharan SK. Mishra AP, et al. Among authors: sharan sk. Nat Commun. 2022 Apr 1;13(1):1751. doi: 10.1038/s41467-022-29409-y. Nat Commun. 2022. PMID: 35365640 Free PMC article.
A novel mouse model of PMS2 founder mutation that causes mismatch repair defect due to aberrant splicing.
Biswas K, Couillard M, Cavallone L, Burkett S, Stauffer S, Martin BK, Southon E, Reid S, Plona TM, Baugher RN, Mellott SD, Pike KM, Albaugh ME, Maedler-Kron C, Hamel N, Tessarollo L, Marcus V, Foulkes WD, Sharan SK. Biswas K, et al. Among authors: sharan sk. Cell Death Dis. 2021 Sep 6;12(9):838. doi: 10.1038/s41419-021-04130-8. Cell Death Dis. 2021. PMID: 34489406 Free PMC article.
96 results