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Integrative Analysis of a Large Real-World Cohort of Small Cell Lung Cancer Identifies Distinct Genetic Subtypes and Insights into Histologic Transformation.
Sivakumar S, Moore JA, Montesion M, Sharaf R, Lin DI, Colón CI, Fleishmann Z, Ebot EM, Newberg JY, Mills JM, Hegde PS, Pan Q, Dowlati A, Frampton GM, Sage J, Lovly CM. Sivakumar S, et al. Among authors: sharaf r. Cancer Discov. 2023 Jul 7;13(7):1572-1591. doi: 10.1158/2159-8290.CD-22-0620. Cancer Discov. 2023. PMID: 37062002 Free PMC article.
The Control of HIV After Antiretroviral Medication Pause (CHAMP) Study: Posttreatment Controllers Identified From 14 Clinical Studies.
Namazi G, Fajnzylber JM, Aga E, Bosch RJ, Acosta EP, Sharaf R, Hartogensis W, Jacobson JM, Connick E, Volberding P, Skiest D, Margolis D, Sneller MC, Little SJ, Gianella S, Smith DM, Kuritzkes DR, Gulick RM, Mellors JW, Mehraj V, Gandhi RT, Mitsuyasu R, Schooley RT, Henry K, Tebas P, Deeks SG, Chun TW, Collier AC, Routy JP, Hecht FM, Walker BD, Li JZ. Namazi G, et al. Among authors: sharaf r. J Infect Dis. 2018 Nov 5;218(12):1954-1963. doi: 10.1093/infdis/jiy479. J Infect Dis. 2018. PMID: 30085241 Free PMC article.
HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers.
Sharaf R, Lee GQ, Sun X, Etemad B, Aboukhater LM, Hu Z, Brumme ZL, Aga E, Bosch RJ, Wen Y, Namazi G, Gao C, Acosta EP, Gandhi RT, Jacobson JM, Skiest D, Margolis DM, Mitsuyasu R, Volberding P, Connick E, Kuritzkes DR, Lederman MM, Yu XG, Lichterfeld M, Li JZ. Sharaf R, et al. J Clin Invest. 2018 Aug 31;128(9):4074-4085. doi: 10.1172/JCI120549. Epub 2018 Aug 20. J Clin Invest. 2018. PMID: 30024859 Free PMC article.
Autologous neutralizing antibodies increase with early antiretroviral therapy and shape HIV rebound after treatment interruption.
Esmaeilzadeh E, Etemad B, Lavine CL, Garneau L, Li Y, Regan J, Wong C, Sharaf R, Connick E, Volberding P, Sagar M, Seaman MS, Li JZ. Esmaeilzadeh E, et al. Among authors: sharaf r. Sci Transl Med. 2023 May 10;15(695):eabq4490. doi: 10.1126/scitranslmed.abq4490. Epub 2023 May 10. Sci Transl Med. 2023. PMID: 37163616 Free PMC article.
Frequency of post treatment control varies by antiretroviral therapy restart and viral load criteria.
Fajnzylber J, Sharaf R, Hutchinson JN, Aga E, Bosch RJ, Hartogensis W, Jacobson JM, Connick E, Volberding P, Skiest DJ, Margolis D, Sneller MC, Little SJ, Gulick RM, Mellors JW, Gandhi RT, Schooley RT, Henry K, Tebas P, Deeks S, Chun TW, Collier AC, Hecht FM, Li JZ; CHAMP study team. Fajnzylber J, et al. Among authors: sharaf r. AIDS. 2021 Nov 1;35(13):2225-2227. doi: 10.1097/QAD.0000000000002978. AIDS. 2021. PMID: 34127579 Free PMC article.
151 results