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Molecular pathophysiology of hepatic glucose production.
Sharabi K, Tavares CD, Rines AK, Puigserver P. Sharabi K, et al. Mol Aspects Med. 2015 Dec;46:21-33. doi: 10.1016/j.mam.2015.09.003. Epub 2015 Nov 5. Mol Aspects Med. 2015. PMID: 26549348 Free PMC article. Review.
The Methionine Transamination Pathway Controls Hepatic Glucose Metabolism through Regulation of the GCN5 Acetyltransferase and the PGC-1α Transcriptional Coactivator.
Tavares CD, Sharabi K, Dominy JE, Lee Y, Isasa M, Orozco JM, Jedrychowski MP, Kamenecka TM, Griffin PR, Gygi SP, Puigserver P. Tavares CD, et al. Among authors: sharabi k. J Biol Chem. 2016 May 13;291(20):10635-45. doi: 10.1074/jbc.M115.706200. Epub 2016 Mar 28. J Biol Chem. 2016. PMID: 27022023 Free PMC article.
Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes.
Sharabi K, Lin H, Tavares CDJ, Dominy JE, Camporez JP, Perry RJ, Schilling R, Rines AK, Lee J, Hickey M, Bennion M, Palmer M, Nag PP, Bittker JA, Perez J, Jedrychowski MP, Ozcan U, Gygi SP, Kamenecka TM, Shulman GI, Schreiber SL, Griffin PR, Puigserver P. Sharabi K, et al. Cell. 2017 Mar 23;169(1):148-160.e15. doi: 10.1016/j.cell.2017.03.001. Cell. 2017. PMID: 28340340 Free PMC article.
Insulin regulation of gluconeogenesis.
Hatting M, Tavares CDJ, Sharabi K, Rines AK, Puigserver P. Hatting M, et al. Among authors: sharabi k. Ann N Y Acad Sci. 2018 Jan;1411(1):21-35. doi: 10.1111/nyas.13435. Epub 2017 Sep 3. Ann N Y Acad Sci. 2018. PMID: 28868790 Free PMC article. Review.
Obesity/Type 2 Diabetes-Associated Liver Tumors Are Sensitive to Cyclin D1 Deficiency.
Luo C, Liang J, Sharabi K, Hatting M, Perry EA, Tavares CDJ, Goyal L, Srivastava A, Bilodeau M, Zhu AX, Sicinski P, Puigserver P. Luo C, et al. Among authors: sharabi k. Cancer Res. 2020 Aug 15;80(16):3215-3221. doi: 10.1158/0008-5472.CAN-20-0106. Epub 2020 Jun 30. Cancer Res. 2020. PMID: 32606000 Free PMC article.
20 results