Shapiro GI - Search Results

1

Targeting DNA Repair with Combined Inhibition of NHEJ and MMEJ Induces Synthetic Lethality in TP53-Mutant Cancers.

Patterson-Fortin J, Bose A, Tsai WC, Grochala C, Nguyen H, Zhou J, Parmar K, Lazaro JB, Liu J, McQueen K, Shapiro GI, Kozono D, D'Andrea AD. Patterson-Fortin J, et al. Among authors: shapiro gi. Cancer Res. 2022 Oct 17;82(20):3815-3829. doi: 10.1158/0008-5472.CAN-22-1124. Cancer Res. 2022. PMID: 35972384 Free PMC article.

2

Reciprocal Rb inactivation and p16INK4 expression in primary lung cancers and cell lines.

Shapiro GI, Edwards CD, Kobzik L, Godleski J, Richards W, Sugarbaker DJ, Rollins BJ. Shapiro GI, et al. Cancer Res. 1995 Feb 1;55(3):505-9. Cancer Res. 1995. PMID: 7834618

3

Multiple mechanisms of p16INK4A inactivation in non-small cell lung cancer cell lines.

Shapiro GI, Park JE, Edwards CD, Mao L, Merlo A, Sidransky D, Ewen ME, Rollins BJ. Shapiro GI, et al. Cancer Res. 1995 Dec 15;55(24):6200-9. Cancer Res. 1995. PMID: 8521414

4

Flavopiridol induces cell cycle arrest and p53-independent apoptosis in non-small cell lung cancer cell lines.

Shapiro GI, Koestner DA, Matranga CB, Rollins BJ. Shapiro GI, et al. Clin Cancer Res. 1999 Oct;5(10):2925-38. Clin Cancer Res. 1999. PMID: 10537362

5

Selective sensitization of transformed cells to flavopiridol-induced apoptosis following recruitment to S-phase.

Matranga CB, Shapiro GI. Matranga CB, et al. Among authors: shapiro gi. Cancer Res. 2002 Mar 15;62(6):1707-17. Cancer Res. 2002. PMID: 11912144

6

Flavopiridol-induced apoptosis during S phase requires E2F-1 and inhibition of cyclin A-dependent kinase activity.

Jiang J, Matranga CB, Cai D, Latham VM Jr, Zhang X, Lowell AM, Martelli F, Shapiro GI. Jiang J, et al. Among authors: shapiro gi. Cancer Res. 2003 Nov 1;63(21):7410-22. Cancer Res. 2003. PMID: 14612540

7

Epidermal growth factor receptors harboring kinase domain mutations associate with the heat shock protein 90 chaperone and are destabilized following exposure to geldanamycins.

Shimamura T, Lowell AM, Engelman JA, Shapiro GI. Shimamura T, et al. Among authors: shapiro gi. Cancer Res. 2005 Jul 15;65(14):6401-8. doi: 10.1158/0008-5472.CAN-05-0933. Cancer Res. 2005. PMID: 16024644

8

AZ703, an imidazo[1,2-a]pyridine inhibitor of cyclin-dependent kinases 1 and 2, induces E2F-1-dependent apoptosis enhanced by depletion of cyclin-dependent kinase 9.

Cai D, Byth KF, Shapiro GI. Cai D, et al. Among authors: shapiro gi. Cancer Res. 2006 Jan 1;66(1):435-44. doi: 10.1158/0008-5472.CAN-05-1769. Cancer Res. 2006. PMID: 16397259

9

Non-small-cell lung cancer and Ba/F3 transformed cells harboring the ERBB2 G776insV_G/C mutation are sensitive to the dual-specific epidermal growth factor receptor and ERBB2 inhibitor HKI-272.

Shimamura T, Ji H, Minami Y, Thomas RK, Lowell AM, Shah K, Greulich H, Glatt KA, Meyerson M, Shapiro GI, Wong KK. Shimamura T, et al. Among authors: shapiro gi. Cancer Res. 2006 Jul 1;66(13):6487-91. doi: 10.1158/0008-5472.CAN-06-0971. Cancer Res. 2006. PMID: 16818618

10

The Aurora kinase inhibitor VX-680 induces endoreduplication and apoptosis preferentially in cells with compromised p53-dependent postmitotic checkpoint function.

Gizatullin F, Yao Y, Kung V, Harding MW, Loda M, Shapiro GI. Gizatullin F, et al. Among authors: shapiro gi. Cancer Res. 2006 Aug 1;66(15):7668-77. doi: 10.1158/0008-5472.CAN-05-3353. Cancer Res. 2006. PMID: 16885368

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