Shanley DP - Search Results

1

Cytosolic Self-DNA-A Potential Source of Chronic Inflammation in Aging.

Akbari M, Shanley DP, Bohr VA, Rasmussen LJ. Akbari M, et al. Among authors: shanley dp. Cells. 2021 Dec 15;10(12):3544. doi: 10.3390/cells10123544. Cells. 2021. PMID: 34944052 Free PMC article. Review.

2

Systems modelling predicts chronic inflammation and genomic instability prevent effective mitochondrial regulation during biological ageing.

Guimera AM, Clark P, Wordsworth J, Anugula S, Rasmussen LJ, Shanley DP. Guimera AM, et al. Among authors: shanley dp. Exp Gerontol. 2022 Sep;166:111889. doi: 10.1016/j.exger.2022.111889. Epub 2022 Jul 7. Exp Gerontol. 2022. PMID: 35811018 Free article. Review.

3

The DNA repair enzyme, aprataxin, plays a role in innate immune signaling.

Madsen HB, Pease LI, Scanlan RL, Akbari M, Rasmussen LJ, Shanley DP, Bohr VA. Madsen HB, et al. Among authors: shanley dp. Front Aging Neurosci. 2023 Dec 15;15:1290681. doi: 10.3389/fnagi.2023.1290681. eCollection 2023. Front Aging Neurosci. 2023. PMID: 38161589 Free PMC article.

4

Towards an e-biology of ageing: integrating theory and data.

Kirkwood TB, Boys RJ, Gillespie CS, Proctor CJ, Shanley DP, Wilkinson DJ. Kirkwood TB, et al. Among authors: shanley dp. Nat Rev Mol Cell Biol. 2003 Mar;4(3):243-9. doi: 10.1038/nrm1051. Nat Rev Mol Cell Biol. 2003. PMID: 12612643

5

Dynamic modelling of pathways to cellular senescence reveals strategies for targeted interventions.

Dalle Pezze P, Nelson G, Otten EG, Korolchuk VI, Kirkwood TB, von Zglinicki T, Shanley DP. Dalle Pezze P, et al. Among authors: shanley dp. PLoS Comput Biol. 2014 Aug 28;10(8):e1003728. doi: 10.1371/journal.pcbi.1003728. eCollection 2014 Aug. PLoS Comput Biol. 2014. PMID: 25166345 Free PMC article.

6

Systems modelling ageing: from single senescent cells to simple multi-cellular models.

Martinez Guimera A, Welsh C, Dalle Pezze P, Fullard N, Nelson G, Roger MF, Przyborski SA, Shanley DP. Martinez Guimera A, et al. Among authors: shanley dp. Essays Biochem. 2017 Jul 11;61(3):369-377. doi: 10.1042/EBC20160087. Print 2017 Jul 15. Essays Biochem. 2017. PMID: 28698310 Free PMC article. Review.

7

Modelling the role of redox-related mechanisms in musculoskeletal ageing.

Guimera AM, Shanley DP, Proctor CJ. Guimera AM, et al. Among authors: shanley dp. Free Radic Biol Med. 2019 Feb 20;132:11-18. doi: 10.1016/j.freeradbiomed.2018.09.013. Epub 2018 Sep 13. Free Radic Biol Med. 2019. PMID: 30219703 Review.

8

Modelling the actions of chaperones and their role in ageing.

Proctor CJ, Soti C, Boys RJ, Gillespie CS, Shanley DP, Wilkinson DJ, Kirkwood TB. Proctor CJ, et al. Among authors: shanley dp. Mech Ageing Dev. 2005 Jan;126(1):119-31. doi: 10.1016/j.mad.2004.09.031. Mech Ageing Dev. 2005. PMID: 15610770

9

A stochastic step model of replicative senescence explains ROS production rate in ageing cell populations.

Lawless C, Jurk D, Gillespie CS, Shanley D, Saretzki G, von Zglinicki T, Passos JF. Lawless C, et al. PLoS One. 2012;7(2):e32117. doi: 10.1371/journal.pone.0032117. Epub 2012 Feb 16. PLoS One. 2012. PMID: 22359661 Free PMC article.

10

Integrated Stochastic Model of DNA Damage Repair by Non-homologous End Joining and p53/p21-Mediated Early Senescence Signalling.

Dolan DW, Zupanic A, Nelson G, Hall P, Miwa S, Kirkwood TB, Shanley DP. Dolan DW, et al. Among authors: shanley dp. PLoS Comput Biol. 2015 May 28;11(5):e1004246. doi: 10.1371/journal.pcbi.1004246. eCollection 2015 May. PLoS Comput Biol. 2015. PMID: 26020242 Free PMC article.

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