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Page 1
The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure.
Cluntun AA, Badolia R, Lettlova S, Parnell KM, Shankar TS, Diakos NA, Olson KA, Taleb I, Tatum SM, Berg JA, Cunningham CN, Van Ry T, Bott AJ, Krokidi AT, Fogarty S, Skedros S, Swiatek WI, Yu X, Luo B, Merx S, Navankasattusas S, Cox JE, Ducker GS, Holland WL, McKellar SH, Rutter J, Drakos SG. Cluntun AA, et al. Among authors: shankar ts. Cell Metab. 2021 Mar 2;33(3):629-648.e10. doi: 10.1016/j.cmet.2020.12.003. Epub 2020 Dec 16. Cell Metab. 2021. PMID: 33333007 Free PMC article.
The human heart contains distinct macrophage subsets with divergent origins and functions.
Bajpai G, Schneider C, Wong N, Bredemeyer A, Hulsmans M, Nahrendorf M, Epelman S, Kreisel D, Liu Y, Itoh A, Shankar TS, Selzman CH, Drakos SG, Lavine KJ. Bajpai G, et al. Among authors: shankar ts. Nat Med. 2018 Aug;24(8):1234-1245. doi: 10.1038/s41591-018-0059-x. Epub 2018 Jun 11. Nat Med. 2018. PMID: 29892064 Free PMC article.
The Role of Nonglycolytic Glucose Metabolism in Myocardial Recovery Upon Mechanical Unloading and Circulatory Support in Chronic Heart Failure.
Badolia R, Ramadurai DKA, Abel ED, Ferrin P, Taleb I, Shankar TS, Krokidi AT, Navankasattusas S, McKellar SH, Yin M, Kfoury AG, Wever-Pinzon O, Fang JC, Selzman CH, Chaudhuri D, Rutter J, Drakos SG. Badolia R, et al. Among authors: shankar ts. Circulation. 2020 Jul 21;142(3):259-274. doi: 10.1161/CIRCULATIONAHA.119.044452. Epub 2020 Apr 30. Circulation. 2020. PMID: 32351122 Free PMC article.
Perm1 regulates cardiac energetics as a downstream target of the histone methyltransferase Smyd1.
Oka SI, Sabry AD, Horiuchi AK, Cawley KM, O'Very SA, Zaitsev MA, Shankar TS, Byun J, Mukai R, Xu X, Torres NS, Kumar A, Yazawa M, Ling J, Taleb I, Saijoh Y, Drakos SG, Sadoshima J, Warren JS. Oka SI, et al. Among authors: shankar ts. PLoS One. 2020 Jun 23;15(6):e0234913. doi: 10.1371/journal.pone.0234913. eCollection 2020. PLoS One. 2020. PMID: 32574189 Free PMC article.
Cardiac-specific deletion of voltage dependent anion channel 2 leads to dilated cardiomyopathy by altering calcium homeostasis.
Shankar TS, Ramadurai DKA, Steinhorst K, Sommakia S, Badolia R, Thodou Krokidi A, Calder D, Navankasattusas S, Sander P, Kwon OS, Aravamudhan A, Ling J, Dendorfer A, Xie C, Kwon O, Cheng EHY, Whitehead KJ, Gudermann T, Richardson RS, Sachse FB, Schredelseker J, Spitzer KW, Chaudhuri D, Drakos SG. Shankar TS, et al. Nat Commun. 2021 Jul 28;12(1):4583. doi: 10.1038/s41467-021-24869-0. Nat Commun. 2021. PMID: 34321484 Free PMC article.
PERM1 regulates energy metabolism in the heart via ERRα/PGC-1α axis.
Oka SI, Sreedevi K, Shankar TS, Yedla S, Arowa S, James A, Stone KG, Olmos K, Sabry AD, Horiuchi A, Cawley KM, O'very SA, Tong M, Byun J, Xu X, Kashyap S, Mourad Y, Vehra O, Calder D, Lunde T, Liu T, Li H, Mashchek JA, Cox J, Saijoh Y, Drakos SG, Warren JS. Oka SI, et al. Among authors: shankar ts. Front Cardiovasc Med. 2022 Nov 7;9:1033457. doi: 10.3389/fcvm.2022.1033457. eCollection 2022. Front Cardiovasc Med. 2022. PMID: 36419485 Free PMC article.
Distinct Transcriptomic and Proteomic Profile Specifies Patients Who Have Heart Failure With Potential of Myocardial Recovery on Mechanical Unloading and Circulatory Support.
Drakos SG, Badolia R, Makaju A, Kyriakopoulos CP, Wever-Pinzon O, Tracy CM, Bakhtina A, Bia R, Parnell T, Taleb I, Ramadurai DKA, Navankasattusas S, Dranow E, Hanff TC, Tseliou E, Shankar TS, Visker J, Hamouche R, Stauder EL, Caine WT, Alharethi R, Selzman CH, Franklin S. Drakos SG, et al. Among authors: shankar ts. Circulation. 2023 Jan 31;147(5):409-424. doi: 10.1161/CIRCULATIONAHA.121.056600. Epub 2022 Nov 30. Circulation. 2023. PMID: 36448446 Free PMC article.
Defining cardiac functional recovery in end-stage heart failure at single-cell resolution.
Amrute JM, Lai L, Ma P, Koenig AL, Kamimoto K, Bredemeyer A, Shankar TS, Kuppe C, Kadyrov FF, Schulte LJ, Stoutenburg D, Kopecky BJ, Navankasattusas S, Visker J, Morris SA, Kramann R, Leuschner F, Mann DL, Drakos SG, Lavine KJ. Amrute JM, et al. Among authors: shankar ts. Nat Cardiovasc Res. 2023 Apr;2(4):399-416. doi: 10.1038/s44161-023-00260-8. Epub 2023 Apr 6. Nat Cardiovasc Res. 2023. PMID: 37583573 Free PMC article.
16 results