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The Pseudo-Natural Product Rhonin Targets RHOGDI.
Akbarzadeh M, Flegel J, Patil S, Shang E, Narayan R, Buchholzer M, Kazemein Jasemi NS, Grigalunas M, Krzyzanowski A, Abegg D, Shuster A, Potowski M, Karatas H, Karageorgis G, Mosaddeghzadeh N, Zischinsky ML, Merten C, Golz C, Brieger L, Strohmann C, Antonchick AP, Janning P, Adibekian A, Goody RS, Ahmadian MR, Ziegler S, Waldmann H. Akbarzadeh M, et al. Among authors: shang e. Angew Chem Int Ed Engl. 2022 Apr 25;61(18):e202115193. doi: 10.1002/anie.202115193. Epub 2022 Mar 2. Angew Chem Int Ed Engl. 2022. PMID: 35170181 Free PMC article.
Discovery of small-molecule modulator of heterotrimeric Gi-protein by integrated phenotypic profiling and chemical proteomics.
Kawamura T, Futamura Y, Shang E, Muroi M, Janning P, Ueno M, Wilke J, Takeda S, Kondoh Y, Ziegler S, Watanabe N, Waldmann H, Osada H. Kawamura T, et al. Among authors: shang e. Biosci Biotechnol Biochem. 2020 Dec;84(12):2484-2490. doi: 10.1080/09168451.2020.1812375. Epub 2020 Aug 31. Biosci Biotechnol Biochem. 2020. PMID: 32867616
Extend the benchmarking indel set by manual review using the individual cell line sequencing data from the Sequencing Quality Control 2 (SEQC2) project.
Gong B, Li D, Zhang Y, Kusko R, Lababidi S, Cao Z, Chen M, Chen N, Chen Q, Chen Q, Dai J, Gan Q, Gao Y, Guo M, Hariani G, He Y, Hou W, Jiang H, Kushwaha G, Li JL, Li J, Li Y, Liu LC, Liu R, Liu S, Meriaux E, Mo M, Moore M, Moss TJ, Niu Q, Patel A, Ren L, Saremi NF, Shang E, Shang J, Song P, Sun S, Urban BJ, Wang D, Wang S, Wen Z, Xiong X, Yang J, Yin L, Zhang C, Zhang R, Bhandari A, Cai W, Eterovic AK, Megherbi DB, Shi T, Suo C, Yu Y, Zheng Y, Novoradovskaya N, Sears RL, Shi L, Jones W, Tong W, Xu J. Gong B, et al. Among authors: shang e. Sci Rep. 2024 Mar 25;14(1):7028. doi: 10.1038/s41598-024-57439-7. Sci Rep. 2024. PMID: 38528062 Free PMC article.
OGDH and Bcl-xL loss causes synthetic lethality in glioblastoma.
Nguyen TT, Torrini C, Shang E, Shu C, Mun JY, Gao Q, Humala N, Akman HO, Zhang G, Westhoff MA, Karpel-Massler G, Bruce JN, Canoll P, Siegelin MD. Nguyen TT, et al. Among authors: shang e. JCI Insight. 2024 Mar 14;9(8):e172565. doi: 10.1172/jci.insight.172565. JCI Insight. 2024. PMID: 38483541 Free article.
Unraveling the pharmacodynamic substances and possible mechanism of Trichosanthis Pericarpium in the treatment of coronary heart disease based on plasma pharmacochemistry, network pharmacology and experimental validation.
Zhang XY, Xia KR, Wang YN, Liu P, Shang EX, Liu CY, Liu YP, Qu D, Li WW, Duan JA, Chen Y, Zhang HQ. Zhang XY, et al. Among authors: shang ex. J Ethnopharmacol. 2024 May 10;325:117869. doi: 10.1016/j.jep.2024.117869. Epub 2024 Feb 9. J Ethnopharmacol. 2024. PMID: 38342153
416 results