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Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice.
Guthrie LM, Soma S, Yuan S, Silva A, Zulkifli M, Snavely TC, Greene HF, Nunez E, Lynch B, De Ville C, Shanbhag V, Lopez FR, Acharya A, Petris MJ, Kim BE, Gohil VM, Sacchettini JC. Guthrie LM, et al. Among authors: shanbhag v. Science. 2020 May 8;368(6491):620-625. doi: 10.1126/science.aaz8899. Science. 2020. PMID: 32381719 Free PMC article.
Copper metabolism as a unique vulnerability in cancer.
Shanbhag VC, Gudekar N, Jasmer K, Papageorgiou C, Singh K, Petris MJ. Shanbhag VC, et al. Biochim Biophys Acta Mol Cell Res. 2021 Feb;1868(2):118893. doi: 10.1016/j.bbamcr.2020.118893. Epub 2020 Oct 20. Biochim Biophys Acta Mol Cell Res. 2021. PMID: 33091507 Free PMC article. Review.
Ceruloplasmin as a source of Cu for a fungal pathogen.
Besold AN, Shanbhag V, Petris MJ, Culotta VC. Besold AN, et al. Among authors: shanbhag v. J Inorg Biochem. 2021 Jun;219:111424. doi: 10.1016/j.jinorgbio.2021.111424. Epub 2021 Mar 15. J Inorg Biochem. 2021. PMID: 33765639 Free PMC article.
FDX1-dependent and independent mechanisms of elesclomol-mediated intracellular copper delivery.
Zulkifli M, Spelbring AN, Zhang Y, Soma S, Chen S, Li L, Le T, Shanbhag V, Petris MJ, Chen TY, Ralle M, Barondeau DP, Gohil VM. Zulkifli M, et al. Among authors: shanbhag v. Proc Natl Acad Sci U S A. 2023 Mar 7;120(10):e2216722120. doi: 10.1073/pnas.2216722120. Epub 2023 Feb 27. Proc Natl Acad Sci U S A. 2023. PMID: 36848556 Free PMC article.
132 results