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Efficacy of tecovirimat (ST-246) in nonhuman primates infected with variola virus (Smallpox).
Mucker EM, Goff AJ, Shamblin JD, Grosenbach DW, Damon IK, Mehal JM, Holman RC, Carroll D, Gallardo N, Olson VA, Clemmons CJ, Hudson P, Hruby DE. Mucker EM, et al. Among authors: shamblin jd. Antimicrob Agents Chemother. 2013 Dec;57(12):6246-53. doi: 10.1128/AAC.00977-13. Epub 2013 Oct 7. Antimicrob Agents Chemother. 2013. PMID: 24100494 Free PMC article.
Immunogenicity of a highly attenuated MVA smallpox vaccine and protection against monkeypox.
Earl PL, Americo JL, Wyatt LS, Eller LA, Whitbeck JC, Cohen GH, Eisenberg RJ, Hartmann CJ, Jackson DL, Kulesh DA, Martinez MJ, Miller DM, Mucker EM, Shamblin JD, Zwiers SH, Huggins JW, Jahrling PB, Moss B. Earl PL, et al. Among authors: shamblin jd. Nature. 2004 Mar 11;428(6979):182-5. doi: 10.1038/nature02331. Nature. 2004. PMID: 15014500
ST-246 antiviral efficacy in a nonhuman primate monkeypox model: determination of the minimal effective dose and human dose justification.
Jordan R, Goff A, Frimm A, Corrado ML, Hensley LE, Byrd CM, Mucker E, Shamblin J, Bolken TC, Wlazlowski C, Johnson W, Chapman J, Twenhafel N, Tyavanagimatt S, Amantana A, Chinsangaram J, Hruby DE, Huggins J. Jordan R, et al. Antimicrob Agents Chemother. 2009 May;53(5):1817-22. doi: 10.1128/AAC.01596-08. Epub 2009 Feb 17. Antimicrob Agents Chemother. 2009. PMID: 19223621 Free PMC article. Clinical Trial.
Nonhuman primates are protected from smallpox virus or monkeypox virus challenges by the antiviral drug ST-246.
Huggins J, Goff A, Hensley L, Mucker E, Shamblin J, Wlazlowski C, Johnson W, Chapman J, Larsen T, Twenhafel N, Karem K, Damon IK, Byrd CM, Bolken TC, Jordan R, Hruby D. Huggins J, et al. Antimicrob Agents Chemother. 2009 Jun;53(6):2620-5. doi: 10.1128/AAC.00021-09. Epub 2009 Apr 6. Antimicrob Agents Chemother. 2009. PMID: 19349521 Free PMC article.
Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak.
Bornholdt ZA, Turner HL, Murin CD, Li W, Sok D, Souders CA, Piper AE, Goff A, Shamblin JD, Wollen SE, Sprague TR, Fusco ML, Pommert KB, Cavacini LA, Smith HL, Klempner M, Reimann KA, Krauland E, Gerngross TU, Wittrup KD, Saphire EO, Burton DR, Glass PJ, Ward AB, Walker LM. Bornholdt ZA, et al. Among authors: shamblin jd. Science. 2016 Mar 4;351(6277):1078-83. doi: 10.1126/science.aad5788. Epub 2016 Feb 18. Science. 2016. PMID: 26912366 Free PMC article.
49 results