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ICOS agonism by JTX-2011 (vopratelimab) requires initial T cell priming and Fc cross-linking for optimal T cell activation and anti-tumor immunity in preclinical models.
Hanson A, Elpek K, Duong E, Shallberg L, Fan M, Johnson C, Wallace M, Mabry GR, Sazinsky S, Pepper L, Shu CJ, Sathyanarayanan S, Zuerndorfer S, Simpson T, Gostissa M, Briskin M, Law D, Michaelson J, Harvey CJ. Hanson A, et al. Among authors: shallberg l. PLoS One. 2020 Sep 24;15(9):e0239595. doi: 10.1371/journal.pone.0239595. eCollection 2020. PLoS One. 2020. PMID: 32970735 Free PMC article.
PD-L1-PD-1 interactions limit effector regulatory T cell populations at homeostasis and during infection.
Perry JA, Shallberg L, Clark JT, Gullicksrud JA, DeLong JH, Douglas BB, Hart AP, Lanzar Z, O'Dea K, Konradt C, Park J, Kuchroo JR, Grubaugh D, Zaretsky AG, Brodsky IE, Malefyt RW, Christian DA, Sharpe AH, Hunter CA. Perry JA, et al. Among authors: shallberg l. Nat Immunol. 2022 May;23(5):743-756. doi: 10.1038/s41590-022-01170-w. Epub 2022 Apr 18. Nat Immunol. 2022. PMID: 35437326 Free PMC article.
Dendritic cell-mediated responses to secreted Cryptosporidium effectors promote parasite-specific CD8+ T cell responses.
Haskins BE, Gullicksrud JA, Wallbank BA, Dumaine JE, Guérin A, Cohn IS, O'Dea KM, Pardy RD, Merolle MI, Shallberg LA, Hunter EN, Byerly JH, Smith EJ, Buenconsejo GY, McLeod BI, Christian DA, Striepen B, Hunter CA. Haskins BE, et al. Among authors: shallberg la. Mucosal Immunol. 2024 Mar 18:S1933-0219(24)00022-9. doi: 10.1016/j.mucimm.2024.03.003. Online ahead of print. Mucosal Immunol. 2024. PMID: 38508522 Free article.
NF-κB Signaling is Required for X-Chromosome Inactivation Maintenance Following T cell Activation.
Forsyth KS, Toothacre NE, Jiwrajka N, Driscoll AM, Shallberg LA, Cunningham-Rundles C, Barmettler S, Farmer J, Verbsky J, Routes J, Beiting DP, Romberg N, May MJ, Anguera MC. Forsyth KS, et al. Among authors: shallberg la. bioRxiv [Preprint]. 2024 Feb 12:2024.02.08.579505. doi: 10.1101/2024.02.08.579505. bioRxiv. 2024. PMID: 38405871 Free PMC article. Preprint.
Dendritic cell-mediated responses to secreted Cryptosporidium effectors are required for parasite-specific CD8 + T cell responses.
Haskins BE, Gullicksrud JA, Wallbank BA, Dumaine JE, Guérin A, Cohn IS, O'Dea KM, Pardy RD, Merolle MI, Shallberg LA, Hunter EN, Byerly JH, Smith EJ, Buenconsejo GY, McLeod BI, Christian DA, Striepen B, Hunter CA. Haskins BE, et al. Among authors: shallberg la. bioRxiv [Preprint]. 2023 Aug 18:2023.08.16.553566. doi: 10.1101/2023.08.16.553566. bioRxiv. 2023. PMID: 37645924 Free PMC article. Updated. Preprint.
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