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Mepolizumab targets multiple immune cells in aspirin-exacerbated respiratory disease.
Buchheit KM, Lewis E, Gakpo D, Hacker J, Sohail A, Taliaferro F, Berreondo Giron E, Asare C, Vukovic M, Bensko JC, Dwyer DF, Shalek AK, Ordovas-Montanes J, Laidlaw TM. Buchheit KM, et al. Among authors: shalek ak. J Allergy Clin Immunol. 2021 Aug;148(2):574-584. doi: 10.1016/j.jaci.2021.05.043. Epub 2021 Jun 16. J Allergy Clin Immunol. 2021. PMID: 34144111 Free PMC article. Clinical Trial.
Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types.
Mead BE, Ordovas-Montanes J, Braun AP, Levy LE, Bhargava P, Szucs MJ, Ammendolia DA, MacMullan MA, Yin X, Hughes TK, Wadsworth MH 2nd, Ahmad R, Rakoff-Nahoum S, Carr SA, Langer R, Collins JJ, Shalek AK, Karp JM. Mead BE, et al. Among authors: shalek ak. BMC Biol. 2018 Jun 5;16(1):62. doi: 10.1186/s12915-018-0527-2. BMC Biol. 2018. PMID: 29871632 Free PMC article.
Allergic inflammatory memory in human respiratory epithelial progenitor cells.
Ordovas-Montanes J, Dwyer DF, Nyquist SK, Buchheit KM, Vukovic M, Deb C, Wadsworth MH 2nd, Hughes TK, Kazer SW, Yoshimoto E, Cahill KN, Bhattacharyya N, Katz HR, Berger B, Laidlaw TM, Boyce JA, Barrett NA, Shalek AK. Ordovas-Montanes J, et al. Among authors: shalek ak. Nature. 2018 Aug;560(7720):649-654. doi: 10.1038/s41586-018-0449-8. Epub 2018 Aug 22. Nature. 2018. PMID: 30135581 Free PMC article.
T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation.
Biton M, Haber AL, Rogel N, Burgin G, Beyaz S, Schnell A, Ashenberg O, Su CW, Smillie C, Shekhar K, Chen Z, Wu C, Ordovas-Montanes J, Alvarez D, Herbst RH, Zhang M, Tirosh I, Dionne D, Nguyen LT, Xifaras ME, Shalek AK, von Andrian UH, Graham DB, Rozenblatt-Rosen O, Shi HN, Kuchroo V, Yilmaz OH, Regev A, Xavier RJ. Biton M, et al. Among authors: shalek ak. Cell. 2018 Nov 15;175(5):1307-1320.e22. doi: 10.1016/j.cell.2018.10.008. Epub 2018 Nov 1. Cell. 2018. PMID: 30392957 Free PMC article.
Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration.
Pepe-Mooney BJ, Dill MT, Alemany A, Ordovas-Montanes J, Matsushita Y, Rao A, Sen A, Miyazaki M, Anakk S, Dawson PA, Ono N, Shalek AK, van Oudenaarden A, Camargo FD. Pepe-Mooney BJ, et al. Among authors: shalek ak. Cell Stem Cell. 2019 Jul 3;25(1):23-38.e8. doi: 10.1016/j.stem.2019.04.004. Epub 2019 May 9. Cell Stem Cell. 2019. PMID: 31080134 Free PMC article.
Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis.
Smillie CS, Biton M, Ordovas-Montanes J, Sullivan KM, Burgin G, Graham DB, Herbst RH, Rogel N, Slyper M, Waldman J, Sud M, Andrews E, Velonias G, Haber AL, Jagadeesh K, Vickovic S, Yao J, Stevens C, Dionne D, Nguyen LT, Villani AC, Hofree M, Creasey EA, Huang H, Rozenblatt-Rosen O, Garber JJ, Khalili H, Desch AN, Daly MJ, Ananthakrishnan AN, Shalek AK, Xavier RJ, Regev A. Smillie CS, et al. Among authors: shalek ak. Cell. 2019 Jul 25;178(3):714-730.e22. doi: 10.1016/j.cell.2019.06.029. Cell. 2019. PMID: 31348891 Free PMC article.
Distribution and storage of inflammatory memory in barrier tissues.
Ordovas-Montanes J, Beyaz S, Rakoff-Nahoum S, Shalek AK. Ordovas-Montanes J, et al. Among authors: shalek ak. Nat Rev Immunol. 2020 May;20(5):308-320. doi: 10.1038/s41577-019-0263-z. Epub 2020 Feb 3. Nat Rev Immunol. 2020. PMID: 32015472 Free PMC article. Review.
IL-5Rα marks nasal polyp IgG4- and IgE-expressing cells in aspirin-exacerbated respiratory disease.
Buchheit KM, Dwyer DF, Ordovas-Montanes J, Katz HR, Lewis E, Vukovic M, Lai J, Bankova LG, Bhattacharyya N, Shalek AK, Barrett NA, Boyce JA, Laidlaw TM. Buchheit KM, et al. Among authors: shalek ak. J Allergy Clin Immunol. 2020 Jun;145(6):1574-1584. doi: 10.1016/j.jaci.2020.02.035. Epub 2020 Mar 19. J Allergy Clin Immunol. 2020. PMID: 32199912 Free PMC article.
173 results