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Drug Self-Aggregation into Nano-Entities Has the Potential to Induce Immune Responses.
Mol Pharm. 2023 Aug 7;20(8):4031-4040. doi: 10.1021/acs.molpharmaceut.3c00196. Epub 2023 Jul 8.
Mol Pharm. 2023.
PMID: 37421372
Revealing Drug Self-Associations into Nano-Entities.
Dlim MM, Shahout FS, Khabir MK, Labonté PP, LaPlante SR.
Dlim MM, et al. Among authors: shahout fs.
ACS Omega. 2019 May 23;4(5):8919-8925. doi: 10.1021/acsomega.9b00667. eCollection 2019 May 31.
ACS Omega. 2019.
PMID: 31459979
Free PMC article.
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Probing the free-state solution behavior of drugs and their tendencies to self-aggregate into nano-entities.
LaPlante SR, Roux V, Shahout F, LaPlante G, Woo S, Denk MM, Larda ST, Ayotte Y.
LaPlante SR, et al. Among authors: shahout f.
Nat Protoc. 2021 Nov;16(11):5250-5273. doi: 10.1038/s41596-021-00612-3. Epub 2021 Oct 27.
Nat Protoc. 2021.
PMID: 34707256
Review.
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Jumping from Fragment to Drug via Smart Scaffolds.
Farahani MD, França TCC, Alapour S, Shahout F, Boulon R, Iddir M, Maddalena M, Ayotte Y, LaPlante SR.
Farahani MD, et al. Among authors: shahout f.
ChemMedChem. 2022 May 18;17(10):e202200092. doi: 10.1002/cmdc.202200092. Epub 2022 Apr 1.
ChemMedChem. 2022.
PMID: 35298873
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Robust Strategy for Hit-to-Lead Discovery: NMR for SAR.
Larda ST, Ayotte Y, Denk MM, Coote P, Heffron G, Bendahan D, Shahout F, Girard N, Iddir M, Bouchard P, Bilodeau F, Woo S, Farmer LJ, LaPlante SR.
Larda ST, et al. Among authors: shahout f.
J Med Chem. 2023 Oct 12;66(19):13416-13427. doi: 10.1021/acs.jmedchem.3c00656. Epub 2023 Sep 21.
J Med Chem. 2023.
PMID: 37732695
Free PMC article.
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