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Exploring transcriptional regulators Ref-1 and STAT3 as therapeutic targets in malignant peripheral nerve sheath tumours.
Gampala S, Shah F, Zhang C, Rhodes SD, Babb O, Grimard M, Wireman RS, Rad E, Calver B, Bai RY, Staedtke V, Hulsey EL, Saadatzadeh MR, Pollok KE, Tong Y, Smith AE, Clapp DW, Tee AR, Kelley MR, Fishel ML. Gampala S, et al. Among authors: shah f. Br J Cancer. 2021 Apr;124(9):1566-1580. doi: 10.1038/s41416-021-01270-8. Epub 2021 Mar 3. Br J Cancer. 2021. PMID: 33658640 Free PMC article.
Ref-1/APE1 Inhibition with Novel Small Molecules Blocks Ocular Neovascularization.
Sardar Pasha SPB, Sishtla K, Sulaiman RS, Park B, Shetty T, Shah F, Fishel ML, Wikel JH, Kelley MR, Corson TW. Sardar Pasha SPB, et al. Among authors: shah f. J Pharmacol Exp Ther. 2018 Oct;367(1):108-118. doi: 10.1124/jpet.118.248088. Epub 2018 Aug 3. J Pharmacol Exp Ther. 2018. PMID: 30076264 Free PMC article.
Identification and Characterization of AES-135, a Hydroxamic Acid-Based HDAC Inhibitor That Prolongs Survival in an Orthotopic Mouse Model of Pancreatic Cancer.
Shouksmith AE, Shah F, Grimard ML, Gawel JM, Raouf YS, Geletu M, Berger-Becvar A, de Araujo ED, Luchman HA, Heaton WL, Bakhshinyan D, Adile AA, Venugopal C, O'Hare T, Deininger MW, Singh SK, Konieczny SF, Weiss S, Fishel ML, Gunning PT. Shouksmith AE, et al. Among authors: shah f. J Med Chem. 2019 Mar 14;62(5):2651-2665. doi: 10.1021/acs.jmedchem.8b01957. Epub 2019 Mar 6. J Med Chem. 2019. PMID: 30776234 Free PMC article.
Combined inhibition of Ref-1 and STAT3 leads to synergistic tumour inhibition in multiple cancers using 3D and in vivo tumour co-culture models.
Caston RA, Shah F, Starcher CL, Wireman R, Babb O, Grimard M, McGeown J, Armstrong L, Tong Y, Pili R, Rupert J, Zimmers TA, Elmi AN, Pollok KE, Motea EA, Kelley MR, Fishel ML. Caston RA, et al. Among authors: shah f. J Cell Mol Med. 2021 Jan;25(2):784-800. doi: 10.1111/jcmm.16132. Epub 2020 Dec 3. J Cell Mol Med. 2021. PMID: 33274592 Free PMC article.
Ref-1 redox activity alters cancer cell metabolism in pancreatic cancer: exploiting this novel finding as a potential target.
Gampala S, Shah F, Lu X, Moon HR, Babb O, Umesh Ganesh N, Sandusky G, Hulsey E, Armstrong L, Mosely AL, Han B, Ivan M, Yeh JJ, Kelley MR, Zhang C, Fishel ML. Gampala S, et al. Among authors: shah f. J Exp Clin Cancer Res. 2021 Aug 10;40(1):251. doi: 10.1186/s13046-021-02046-x. J Exp Clin Cancer Res. 2021. PMID: 34376225 Free PMC article.
Correction: Exploring transcriptional regulators Ref-1 and STAT3 as therapeutic targets in malignant peripheral nerve sheath tumours.
Gampala S, Shah F, Zhang C, Rhodes SD, Babb O, Grimard M, Wireman RS, Rad E, Calver B, Bai RY, Staedtke V, Hulsey EL, Saadatzadeh MR, Pollok KE, Tong Y, Smith AE, Clapp DW, Tee AR, Kelley MR, Fishel ML. Gampala S, et al. Among authors: shah f. Br J Cancer. 2022 Oct;127(7):1378-1379. doi: 10.1038/s41416-022-01938-9. Br J Cancer. 2022. PMID: 35953714 Free PMC article. No abstract available.
883 results