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PD-1 up-regulation on CD4+ T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production.
Celada LJ, Kropski JA, Herazo-Maya JD, Luo W, Creecy A, Abad AT, Chioma OS, Lee G, Hassell NE, Shaginurova GI, Wang Y, Johnson JE, Kerrigan A, Mason WR, Baughman RP, Ayers GD, Bernard GR, Culver DA, Montgomery CG, Maher TM, Molyneaux PL, Noth I, Mutsaers SE, Prele CM, Peebles RS Jr, Newcomb DC, Kaminski N, Blackwell TS, Van Kaer L, Drake WP. Celada LJ, et al. Among authors: shaginurova gi. Sci Transl Med. 2018 Sep 26;10(460):eaar8356. doi: 10.1126/scitranslmed.aar8356. Sci Transl Med. 2018. PMID: 30257954 Free PMC article.
Blockade of the programmed death-1 pathway restores sarcoidosis CD4(+) T-cell proliferative capacity.
Braun NA, Celada LJ, Herazo-Maya JD, Abraham S, Shaginurova G, Sevin CM, Grutters J, Culver DA, Dworski R, Sheller J, Massion PP, Polosukhin VV, Johnson JE, Kaminski N, Wilkes DS, Oswald-Richter KA, Drake WP. Braun NA, et al. Am J Respir Crit Care Med. 2014 Sep 1;190(5):560-71. doi: 10.1164/rccm.201401-0188OC. Am J Respir Crit Care Med. 2014. PMID: 25073001 Free PMC article.
Profiles of Long Noncoding RNAs in Human Naive and Memory T Cells.
Spurlock CF 3rd, Shaginurova G, Tossberg JT, Hester JD, Chapman N, Guo Y, Crooke PS 3rd, Aune TM. Spurlock CF 3rd, et al. J Immunol. 2017 Jul 15;199(2):547-558. doi: 10.4049/jimmunol.1700232. Epub 2017 Jun 9. J Immunol. 2017. PMID: 28600289 Free PMC article.