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Genetic screening for single-cell variability modulators driving therapy resistance.
Torre EA, Arai E, Bayatpour S, Jiang CL, Beck LE, Emert BL, Shaffer SM, Mellis IA, Fane ME, Alicea GM, Budinich KA, Weeraratna AT, Shi J, Raj A. Torre EA, et al. Among authors: shaffer sm. Nat Genet. 2021 Jan;53(1):76-85. doi: 10.1038/s41588-020-00749-z. Epub 2021 Jan 4. Nat Genet. 2021. PMID: 33398196 Free PMC article.
Turbo FISH: a method for rapid single molecule RNA FISH.
Shaffer SM, Wu MT, Levesque MJ, Raj A. Shaffer SM, et al. PLoS One. 2013 Sep 16;8(9):e75120. doi: 10.1371/journal.pone.0075120. eCollection 2013. PLoS One. 2013. PMID: 24066168 Free PMC article.
Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance.
Shaffer SM, Dunagin MC, Torborg SR, Torre EA, Emert B, Krepler C, Beqiri M, Sproesser K, Brafford PA, Xiao M, Eggan E, Anastopoulos IN, Vargas-Garcia CA, Singh A, Nathanson KL, Herlyn M, Raj A. Shaffer SM, et al. Nature. 2017 Jun 15;546(7658):431-435. doi: 10.1038/nature22794. Epub 2017 Jun 7. Nature. 2017. PMID: 28607484 Free PMC article.
SAVER: gene expression recovery for single-cell RNA sequencing.
Huang M, Wang J, Torre E, Dueck H, Shaffer S, Bonasio R, Murray JI, Raj A, Li M, Zhang NR. Huang M, et al. Nat Methods. 2018 Jul;15(7):539-542. doi: 10.1038/s41592-018-0033-z. Epub 2018 Jun 25. Nat Methods. 2018. PMID: 29941873 Free PMC article.
Gene expression distribution deconvolution in single-cell RNA sequencing.
Wang J, Huang M, Torre E, Dueck H, Shaffer S, Murray J, Raj A, Li M, Zhang NR. Wang J, et al. Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):E6437-E6446. doi: 10.1073/pnas.1721085115. Epub 2018 Jun 26. Proc Natl Acad Sci U S A. 2018. PMID: 29946020 Free PMC article.
TooManyCells identifies and visualizes relationships of single-cell clades.
Schwartz GW, Zhou Y, Petrovic J, Fasolino M, Xu L, Shaffer SM, Pear WS, Vahedi G, Faryabi RB. Schwartz GW, et al. Among authors: shaffer sm. Nat Methods. 2020 Apr;17(4):405-413. doi: 10.1038/s41592-020-0748-5. Epub 2020 Mar 2. Nat Methods. 2020. PMID: 32123397 Free PMC article.
50 results