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A novel transgenic mouse model of lysosomal storage disorder.
Ortiz-Miranda S, Ji R, Jurczyk A, Aryee KE, Mo S, Fletcher T, Shaffer SA, Greiner DL, Bortell R, Gregg RG, Cheng A, Hennings LJ, Rittenhouse AR. Ortiz-Miranda S, et al. Among authors: shaffer sa. Am J Physiol Gastrointest Liver Physiol. 2016 Nov 1;311(5):G903-G919. doi: 10.1152/ajpgi.00313.2015. Epub 2016 Sep 22. Am J Physiol Gastrointest Liver Physiol. 2016. PMID: 27659423 Free PMC article.
Mass Spectrometry Analysis of Wild-Type and Knock-in Q140/Q140 Huntington's Disease Mouse Brains Reveals Changes in Glycerophospholipids Including Alterations in Phosphatidic Acid and Lyso-Phosphatidic Acid.
Vodicka P, Mo S, Tousley A, Green KM, Sapp E, Iuliano M, Sadri-Vakili G, Shaffer SA, Aronin N, DiFiglia M, Kegel-Gleason KB. Vodicka P, et al. Among authors: shaffer sa. J Huntingtons Dis. 2015;4(2):187-201. doi: 10.3233/JHD-150149. J Huntingtons Dis. 2015. PMID: 26397899
Extracellular vesicles from mice with alcoholic liver disease carry a distinct protein cargo and induce macrophage activation through heat shock protein 90.
Saha B, Momen-Heravi F, Furi I, Kodys K, Catalano D, Gangopadhyay A, Haraszti R, Satishchandran A, Iracheta-Vellve A, Adejumo A, Shaffer SA, Szabo G. Saha B, et al. Among authors: shaffer sa. Hepatology. 2018 May;67(5):1986-2000. doi: 10.1002/hep.29732. Epub 2018 Apr 6. Hepatology. 2018. PMID: 29251792 Free PMC article.
The Dendritic Cell Major Histocompatibility Complex II (MHC II) Peptidome Derives from a Variety of Processing Pathways and Includes Peptides with a Broad Spectrum of HLA-DM Sensitivity.
Clement CC, Becerra A, Yin L, Zolla V, Huang L, Merlin S, Follenzi A, Shaffer SA, Stern LJ, Santambrogio L. Clement CC, et al. Among authors: shaffer sa. J Biol Chem. 2016 Mar 11;291(11):5576-5595. doi: 10.1074/jbc.M115.655738. Epub 2016 Jan 6. J Biol Chem. 2016. PMID: 26740625 Free PMC article.
Serine/threonine acetylation of TGFβ-activated kinase (TAK1) by Yersinia pestis YopJ inhibits innate immune signaling.
Paquette N, Conlon J, Sweet C, Rus F, Wilson L, Pereira A, Rosadini CV, Goutagny N, Weber AN, Lane WS, Shaffer SA, Maniatis S, Fitzgerald KA, Stuart L, Silverman N. Paquette N, et al. Among authors: shaffer sa. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12710-5. doi: 10.1073/pnas.1008203109. Epub 2012 Jul 16. Proc Natl Acad Sci U S A. 2012. PMID: 22802624 Free PMC article.
Striatal synaptosomes from Hdh140Q/140Q knock-in mice have altered protein levels, novel sites of methionine oxidation, and excess glutamate release after stimulation.
Valencia A, Sapp E, Kimm JS, McClory H, Ansong KA, Yohrling G, Kwak S, Kegel KB, Green KM, Shaffer SA, Aronin N, DiFiglia M. Valencia A, et al. Among authors: shaffer sa. J Huntingtons Dis. 2013;2(4):459-75. doi: 10.3233/JHD-130080. J Huntingtons Dis. 2013. PMID: 24696705 Free PMC article.
167 results