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Page 1
The fungal mycobiome promotes pancreatic oncogenesis via activation of MBL.
Aykut B, Pushalkar S, Chen R, Li Q, Abengozar R, Kim JI, Shadaloey SA, Wu D, Preiss P, Verma N, Guo Y, Saxena A, Vardhan M, Diskin B, Wang W, Leinwand J, Kurz E, Kochen Rossi JA, Hundeyin M, Zambrinis C, Li X, Saxena D, Miller G. Aykut B, et al. Among authors: shadaloey sa. Nature. 2019 Oct;574(7777):264-267. doi: 10.1038/s41586-019-1608-2. Epub 2019 Oct 2. Nature. 2019. PMID: 31578522 Free PMC article.
Exercise-induced engagement of the IL-15/IL-15Rα axis promotes anti-tumor immunity in pancreatic cancer.
Kurz E, Hirsch CA, Dalton T, Shadaloey SA, Khodadadi-Jamayran A, Miller G, Pareek S, Rajaei H, Mohindroo C, Baydogan S, Ngo-Huang A, Parker N, Katz MHG, Petzel M, Vucic E, McAllister F, Schadler K, Winograd R, Bar-Sagi D. Kurz E, et al. Among authors: shadaloey sa. Cancer Cell. 2022 Jul 11;40(7):720-737.e5. doi: 10.1016/j.ccell.2022.05.006. Epub 2022 Jun 2. Cancer Cell. 2022. PMID: 35660135 Free PMC article.
Correction to: BTLA+CD200+ B cells dictate the divergent immune landscape and immunotherapeutic resistance in metastatic vs. primary pancreatic cancer.
Diskin B, Adam S, Soto GS, Liria M, Aykut B, Sundberg B, Li E, Leinwand J, Chen R, Kim M, Salas RD, Cassini MF, Buttar C, Wang W, Farooq MS, Shadaloey SAA, Werba G, Fnu A, Yang F, Hirsch C, Glinski J, Panjwani A, Weitzner Y, Cohen D, Asghar U, Miller G. Diskin B, et al. Among authors: shadaloey saa. Oncogene. 2023 Feb;42(8):625. doi: 10.1038/s41388-023-02606-9. Oncogene. 2023. PMID: 36707621 No abstract available.
BTLA+CD200+ B cells dictate the divergent immune landscape and immunotherapeutic resistance in metastatic vs. primary pancreatic cancer.
Diskin B, Adam S, Soto GS, Liria M, Aykut B, Sundberg B, Li E, Leinwand J, Chen R, Kim M, Salas RD, Cassini MF, Buttar C, Wang W, Farooq MS, Shadaloey SAA, Werba G, Fnu A, Yang F, Hirsch C, Glinski J, Panjwani A, Weitzner Y, Cohen D, Asghar U, Miller G. Diskin B, et al. Among authors: shadaloey saa. Oncogene. 2022 Sep;41(38):4349-4360. doi: 10.1038/s41388-022-02425-4. Epub 2022 Aug 10. Oncogene. 2022. PMID: 35948648
Melanoma-Secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis.
Kleffman K, Levinson G, Rose IVL, Blumenberg LM, Shadaloey SAA, Dhabaria A, Wong E, Galán-Echevarría F, Karz A, Argibay D, Von Itter R, Floristán A, Baptiste G, Eskow NM, Tranos JA, Chen J, Vega Y Saenz de Miera EC, Call M, Rogers R, Jour G, Wadghiri YZ, Osman I, Li YM, Mathews P, DeMattos RB, Ueberheide B, Ruggles KV, Liddelow SA, Schneider RJ, Hernando E. Kleffman K, et al. Among authors: shadaloey saa. Cancer Discov. 2022 May 2;12(5):1314-1335. doi: 10.1158/2159-8290.CD-21-1006. Cancer Discov. 2022. PMID: 35262173 Free PMC article.
The histone demethylase PHF8 regulates TGFβ signaling and promotes melanoma metastasis.
Moubarak RS, de Pablos-Aragoneses A, Ortiz-Barahona V, Gong Y, Gowen M, Dolgalev I, Shadaloey SAA, Argibay D, Karz A, Von Itter R, Vega-Sáenz de Miera EC, Sokolova E, Darvishian F, Tsirigos A, Osman I, Hernando E. Moubarak RS, et al. Among authors: shadaloey saa. Sci Adv. 2022 Feb 18;8(7):eabi7127. doi: 10.1126/sciadv.abi7127. Epub 2022 Feb 18. Sci Adv. 2022. PMID: 35179962 Free PMC article.
Intrahepatic microbes govern liver immunity by programming NKT cells.
Leinwand JC, Paul B, Chen R, Xu F, Sierra MA, Paluru MM, Nanduri S, Alcantara CG, Shadaloey SA, Yang F, Adam SA, Li Q, Bandel M, Gakhal I, Appiah L, Guo Y, Vardhan M, Flaminio Z, Grodman ER, Mermelstein A, Wang W, Diskin B, Aykut B, Khan M, Werba G, Pushalkar S, McKinstry M, Kluger Z, Park JJ, Hsieh B, Dancel-Manning K, Liang FX, Park JS, Saxena A, Li X, Theise ND, Saxena D, Miller G. Leinwand JC, et al. Among authors: shadaloey sa. J Clin Invest. 2022 Apr 15;132(8):e151725. doi: 10.1172/JCI151725. J Clin Invest. 2022. PMID: 35175938 Free PMC article.
Targeting Piezo1 unleashes innate immunity against cancer and infectious disease.
Aykut B, Chen R, Kim JI, Wu D, Shadaloey SAA, Abengozar R, Preiss P, Saxena A, Pushalkar S, Leinwand J, Diskin B, Wang W, Werba G, Berman M, Lee SKB, Khodadadi-Jamayran A, Saxena D, Coetzee WA, Miller G. Aykut B, et al. Among authors: shadaloey saa. Sci Immunol. 2020 Aug 21;5(50):eabb5168. doi: 10.1126/sciimmunol.abb5168. Sci Immunol. 2020. PMID: 32826342
PD-L1 engagement on T cells promotes self-tolerance and suppression of neighboring macrophages and effector T cells in cancer.
Diskin B, Adam S, Cassini MF, Sanchez G, Liria M, Aykut B, Buttar C, Li E, Sundberg B, Salas RD, Chen R, Wang J, Kim M, Farooq MS, Nguy S, Fedele C, Tang KH, Chen T, Wang W, Hundeyin M, Rossi JAK, Kurz E, Haq MIU, Karlen J, Kruger E, Sekendiz Z, Wu D, Shadaloey SAA, Baptiste G, Werba G, Selvaraj S, Loomis C, Wong KK, Leinwand J, Miller G. Diskin B, et al. Among authors: shadaloey saa. Nat Immunol. 2020 Apr;21(4):442-454. doi: 10.1038/s41590-020-0620-x. Epub 2020 Mar 9. Nat Immunol. 2020. PMID: 32152508
Targeting SYK signaling in myeloid cells protects against liver fibrosis and hepatocarcinogenesis.
Torres-Hernandez A, Wang W, Nikiforov Y, Tejada K, Torres L, Kalabin A, Wu Y, Haq MIU, Khan MY, Zhao Z, Su W, Camargo J, Hundeyin M, Diskin B, Adam S, Rossi JAK, Kurz E, Aykut B, Shadaloey SAA, Leinwand J, Miller G. Torres-Hernandez A, et al. Among authors: shadaloey saa. Oncogene. 2019 Jun;38(23):4512-4526. doi: 10.1038/s41388-019-0734-5. Epub 2019 Feb 11. Oncogene. 2019. PMID: 30742098