Seyler C - Search Results

1

Verapamil inhibits Kir2.3 channels by binding to the pore and interfering with PIP₂ binding.

Xynogalos P, Rahm AK, Fried S, Chasan S, Scherer D, Seyler C, Katus HA, Frey N, Zitron E. Xynogalos P, et al. Among authors: seyler c. Naunyn Schmiedebergs Arch Pharmacol. 2023 Apr;396(4):659-667. doi: 10.1007/s00210-022-02342-z. Epub 2022 Nov 29. Naunyn Schmiedebergs Arch Pharmacol. 2023. PMID: 36445385 Free PMC article.

2

Inhibition of cardiac Kv1.5 and Kv4.3 potassium channels by the class Ia anti-arrhythmic ajmaline: mode of action.

Fischer F, Vonderlin N, Zitron E, Seyler C, Scherer D, Becker R, Katus HA, Scholz EP. Fischer F, et al. Among authors: seyler c. Naunyn Schmiedebergs Arch Pharmacol. 2013 Nov;386(11):991-9. doi: 10.1007/s00210-013-0901-0. Epub 2013 Jul 6. Naunyn Schmiedebergs Arch Pharmacol. 2013. PMID: 23832378

3

Isoenzyme-specific regulation of cardiac Kv1.5/Kvβ1.2 ion channel complex by protein kinase C: central role of PKCβII.

Fischer F, Vonderlin N, Seyler C, Zitron E, Korkmaz S, Szabó G, Thomas D, Katus HA, Scholz EP. Fischer F, et al. Among authors: seyler c. Naunyn Schmiedebergs Arch Pharmacol. 2014 May;387(5):469-76. doi: 10.1007/s00210-014-0965-5. Epub 2014 Feb 28. Naunyn Schmiedebergs Arch Pharmacol. 2014. PMID: 24682423

4

Class III antiarrhythmic drug dronedarone inhibits cardiac inwardly rectifying Kir2.1 channels through binding at residue E224.

Xynogalos P, Seyler C, Scherer D, Koepple C, Scholz EP, Thomas D, Katus HA, Zitron E. Xynogalos P, et al. Among authors: seyler c. Naunyn Schmiedebergs Arch Pharmacol. 2014 Dec;387(12):1153-61. doi: 10.1007/s00210-014-1045-6. Epub 2014 Sep 4. Naunyn Schmiedebergs Arch Pharmacol. 2014. PMID: 25182566

5

Dual Mechanism for Inhibition of Inwardly Rectifying Kir2.x Channels by Quinidine Involving Direct Pore Block and PIP₂-interference.

Koepple C, Scherer D, Seyler C, Scholz E, Thomas D, Katus HA, Zitron E. Koepple C, et al. Among authors: seyler c. J Pharmacol Exp Ther. 2017 May;361(2):209-218. doi: 10.1124/jpet.116.238287. Epub 2017 Feb 10. J Pharmacol Exp Ther. 2017. PMID: 28188270

6

Role of plasma membrane-associated AKAPs for the regulation of cardiac I_K1 current by protein kinase A.

Seyler C, Scherer D, Köpple C, Kulzer M, Korkmaz S, Xynogalos P, Thomas D, Kaya Z, Scholz E, Backs J, Karle C, Katus HA, Zitron E. Seyler C, et al. Naunyn Schmiedebergs Arch Pharmacol. 2017 May;390(5):493-503. doi: 10.1007/s00210-017-1344-9. Epub 2017 Mar 22. Naunyn Schmiedebergs Arch Pharmacol. 2017. PMID: 28331977

7

Inhibition of inwardly rectifying Kir2.x channels by the novel anti-cancer agent gambogic acid depends on both pore block and PIP₂ interference.

Scherer D, Schworm B, Seyler C, Xynogalos P, Scholz EP, Thomas D, Katus HA, Zitron E. Scherer D, et al. Among authors: seyler c. Naunyn Schmiedebergs Arch Pharmacol. 2017 Jul;390(7):701-710. doi: 10.1007/s00210-017-1372-5. Epub 2017 Apr 2. Naunyn Schmiedebergs Arch Pharmacol. 2017. PMID: 28365825

8

Selective noradrenaline reuptake inhibitor atomoxetine directly blocks hERG currents.

Scherer D, Hassel D, Bloehs R, Zitron E, von Löwenstern K, Seyler C, Thomas D, Konrad F, Bürgers HF, Seemann G, Rottbauer W, Katus HA, Karle CA, Scholz EP. Scherer D, et al. Among authors: seyler c. Br J Pharmacol. 2009 Jan;156(2):226-36. doi: 10.1111/j.1476-5381.2008.00018.x. Epub 2009 Jan 16. Br J Pharmacol. 2009. PMID: 19154426 Free PMC article.

9

Biophysical properties of zebrafish ether-à-go-go related gene potassium channels.

Scholz EP, Niemer N, Hassel D, Zitron E, Bürgers HF, Bloehs R, Seyler C, Scherer D, Thomas D, Kathöfer S, Katus HA, Rottbauer WA, Karle CA. Scholz EP, et al. Among authors: seyler c. Biochem Biophys Res Commun. 2009 Apr 3;381(2):159-64. doi: 10.1016/j.bbrc.2009.02.042. Epub 2009 Feb 14. Biochem Biophys Res Commun. 2009. PMID: 19232322

10

Inhibition of cardiac Kir2.1-2.3 channels by beta3 adrenoreceptor antagonist SR 59230A.

Kulzer M, Seyler C, Welke F, Scherer D, Xynogalos P, Scholz EP, Thomas D, Becker R, Karle CA, Katus HA, Zitron E. Kulzer M, et al. Among authors: seyler c. Biochem Biophys Res Commun. 2012 Jul 27;424(2):315-20. doi: 10.1016/j.bbrc.2012.06.114. Epub 2012 Jun 27. Biochem Biophys Res Commun. 2012. PMID: 22749993

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