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A Useful and Sustainable Role for N-of-1 Trials in the Healthcare Ecosystem.
Selker HP, Cohen T, D'Agostino RB, Dere WH, Ghaemi SN, Honig PK, Kaitin KI, Kaplan HC, Kravitz RL, Larholt K, McElwee NE, Oye KA, Palm ME, Perfetto E, Ramanathan C, Schmid CH, Seyfert-Margolis V, Trusheim M, Eichler HG. Selker HP, et al. Among authors: seyfert margolis v. Clin Pharmacol Ther. 2022 Aug;112(2):224-232. doi: 10.1002/cpt.2425. Epub 2021 Oct 20. Clin Pharmacol Ther. 2022. PMID: 34551122 Free PMC article. Review.
Efficacy and Effectiveness Too Trials: Clinical Trial Designs to Generate Evidence on Efficacy and on Effectiveness in Wide Practice.
Selker HP, Eichler HG, Stockbridge NL, McElwee NE, Dere WH, Cohen T, Erban JK, Seyfert-Margolis VL, Honig PK, Kaitin KI, Oye KA, D'Agostino RB Sr. Selker HP, et al. Among authors: seyfert margolis vl. Clin Pharmacol Ther. 2019 Apr;105(4):857-866. doi: 10.1002/cpt.1347. Epub 2019 Feb 12. Clin Pharmacol Ther. 2019. PMID: 30610746 Free PMC article.
Adaptive licensing: taking the next step in the evolution of drug approval.
Eichler HG, Oye K, Baird LG, Abadie E, Brown J, Drum CL, Ferguson J, Garner S, Honig P, Hukkelhoven M, Lim JC, Lim R, Lumpkin MM, Neil G, O'Rourke B, Pezalla E, Shoda D, Seyfert-Margolis V, Sigal EV, Sobotka J, Tan D, Unger TF, Hirsch G. Eichler HG, et al. Clin Pharmacol Ther. 2012 Mar;91(3):426-37. doi: 10.1038/clpt.2011.345. Epub 2012 Feb 15. Clin Pharmacol Ther. 2012. PMID: 22336591 Review.
The evidence gap.
Seyfert-Margolis V. Seyfert-Margolis V. Nat Biotechnol. 2018 Mar 6;36(3):228-232. doi: 10.1038/nbt.4097. Nat Biotechnol. 2018. PMID: 29509737 No abstract available.
Community crystal gazing.
Acharya A, Bingham K, Bradner J, Burke W, Charo RA, Cherry J, Choulika A, Coles T, Cook-Deegan R, Crooke ST, Díaz E, Erickson B, Giddings LV, Giwa SE, Greenwood JC, Gulati V, Hall S, Harris J, Heywood J, Hill C, Levin J, Mangubat A, Maraganore J, Mariggi G, Mazur BJ, McGuire AL, Moll N, Moreno J, Naughton G, Nelsen L, Osbourn J, Perez D, Reed J, Schmidt E, Seyfert-Margolis V, Stoffels P, Thorball J, O'Toole T, Vainu I, van Deventer S, Zerhouni E, Zohar D. Acharya A, et al. Nat Biotechnol. 2016 Mar;34(3):276-83. doi: 10.1038/nbt.3515. Nat Biotechnol. 2016. PMID: 26963550 No abstract available.
Erratum: Community crystal gazing.
Acharya A, Bingham K, Bradner J, Burke W, Charo RA, Cherry J, Choulika A, Coles T, Cook-Deegan R, Crook ST, Díaz E, Erickson B, Giddings LV, Giwa SE, Greenwood JC, Gulati V, Hall S, Harris J, Heywood J, Hill C, Levin J, Mangubat A, Maraganore J, Mariggi G, Mazur BJ, McGuire AL, Moll N, Moreno J, Naughton G, Nelsen L, Osbourn J, Perez D, Reed J, Schmidt E, Seyfert-Margolis V, Stoffels P, Thorball J, O'Toole T, Vainu I, van Deventer S, Zerhouni E, Zohar D. Acharya A, et al. Nat Biotechnol. 2016 Jun 9;34(6):666. doi: 10.1038/nbt0616-666d. Nat Biotechnol. 2016. PMID: 27281427 No abstract available.
Rituximab versus cyclophosphamide for ANCA-associated vasculitis.
Stone JH, Merkel PA, Spiera R, Seo P, Langford CA, Hoffman GS, Kallenberg CG, St Clair EW, Turkiewicz A, Tchao NK, Webber L, Ding L, Sejismundo LP, Mieras K, Weitzenkamp D, Ikle D, Seyfert-Margolis V, Mueller M, Brunetta P, Allen NB, Fervenza FC, Geetha D, Keogh KA, Kissin EY, Monach PA, Peikert T, Stegeman C, Ytterberg SR, Specks U; RAVE-ITN Research Group. Stone JH, et al. N Engl J Med. 2010 Jul 15;363(3):221-32. doi: 10.1056/NEJMoa0909905. N Engl J Med. 2010. PMID: 20647199 Free PMC article. Clinical Trial.
34 results