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Page 1
Phospho-Profiling Linking Biology and Clinics in Pediatric Acute Myeloid Leukemia.
Schumich A, Prchal-Murphy M, Maurer-Granofszky M, Hoelbl-Kovacic A, Mühlegger N, Pötschger U, Fajmann S, Haas OA, Nebral K, von Neuhoff N, Zimmermann M, Boztug H, Rasche M, Dolezal M, Walter C, Reinhardt D, Sexl V, Dworzak MN. Schumich A, et al. Among authors: sexl v. Hemasphere. 2019 Dec 16;4(1):e312. doi: 10.1097/HS9.0000000000000312. eCollection 2020 Feb. Hemasphere. 2019. PMID: 32072137 Free PMC article.
Leukemic challenge unmasks a requirement for PI3Kdelta in NK cell-mediated tumor surveillance.
Zebedin E, Simma O, Schuster C, Putz EM, Fajmann S, Warsch W, Eckelhart E, Stoiber D, Weisz E, Schmid JA, Pickl WF, Baumgartner C, Valent P, Piekorz RP, Freissmuth M, Sexl V. Zebedin E, et al. Among authors: sexl v. Blood. 2008 Dec 1;112(12):4655-64. doi: 10.1182/blood-2008-02-139105. Epub 2008 Aug 6. Blood. 2008. PMID: 18684865 Free article.
Stat5 is indispensable for the maintenance of bcr/abl-positive leukaemia.
Hoelbl A, Schuster C, Kovacic B, Zhu B, Wickre M, Hoelzl MA, Fajmann S, Grebien F, Warsch W, Stengl G, Hennighausen L, Poli V, Beug H, Moriggl R, Sexl V. Hoelbl A, et al. Among authors: sexl v. EMBO Mol Med. 2010 Mar;2(3):98-110. doi: 10.1002/emmm.201000062. EMBO Mol Med. 2010. PMID: 20201032 Free PMC article.
Stat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformation.
Friedbichler K, Kerenyi MA, Kovacic B, Li G, Hoelbl A, Yahiaoui S, Sexl V, Müllner EW, Fajmann S, Cerny-Reiterer S, Valent P, Beug H, Gouilleux F, Bunting KD, Moriggl R. Friedbichler K, et al. Among authors: sexl v. Blood. 2010 Sep 2;116(9):1548-58. doi: 10.1182/blood-2009-12-258913. Epub 2010 May 27. Blood. 2010. PMID: 20508164 Free PMC article.
High STAT5 levels mediate imatinib resistance and indicate disease progression in chronic myeloid leukemia.
Warsch W, Kollmann K, Eckelhart E, Fajmann S, Cerny-Reiterer S, Hölbl A, Gleixner KV, Dworzak M, Mayerhofer M, Hoermann G, Herrmann H, Sillaber C, Egger G, Valent P, Moriggl R, Sexl V. Warsch W, et al. Among authors: sexl v. Blood. 2011 Mar 24;117(12):3409-20. doi: 10.1182/blood-2009-10-248211. Epub 2011 Jan 10. Blood. 2011. PMID: 21220747 Free article.
PI3Kδ is essential for tumor clearance mediated by cytotoxic T lymphocytes.
Putz EM, Prchal-Murphy M, Simma OA, Forster F, Koenig X, Stockinger H, Piekorz RP, Freissmuth M, Müller M, Sexl V, Zebedin-Brandl E. Putz EM, et al. Among authors: sexl v. PLoS One. 2012;7(7):e40852. doi: 10.1371/journal.pone.0040852. Epub 2012 Jul 13. PLoS One. 2012. PMID: 22808277 Free PMC article.
Targeting PI3Kδ: One man's meat is another man's poison.
Prchal-Murphy M, Putz EM, Freissmuth M, Sexl V, Zebedin-Brandl E. Prchal-Murphy M, et al. Among authors: sexl v. Oncoimmunology. 2013 Jan 1;2(1):e22272. doi: 10.4161/onci.22272. Oncoimmunology. 2013. PMID: 23482629 Free PMC article.
A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis.
Kollmann K, Heller G, Schneckenleithner C, Warsch W, Scheicher R, Ott RG, Schäfer M, Fajmann S, Schlederer M, Schiefer AI, Reichart U, Mayerhofer M, Hoeller C, Zöchbauer-Müller S, Kerjaschki D, Bock C, Kenner L, Hoefler G, Freissmuth M, Green AR, Moriggl R, Busslinger M, Malumbres M, Sexl V. Kollmann K, et al. Among authors: sexl v. Cancer Cell. 2013 Aug 12;24(2):167-81. doi: 10.1016/j.ccr.2013.07.012. Cancer Cell. 2013. PMID: 23948297 Free PMC article.
PAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesis.
Berger A, Hoelbl-Kovacic A, Bourgeais J, Hoefling L, Warsch W, Grundschober E, Uras IZ, Menzl I, Putz EM, Hoermann G, Schuster C, Fajmann S, Leitner E, Kubicek S, Moriggl R, Gouilleux F, Sexl V. Berger A, et al. Among authors: sexl v. Leukemia. 2014 Mar;28(3):629-41. doi: 10.1038/leu.2013.351. Epub 2013 Nov 22. Leukemia. 2014. PMID: 24263804 Free PMC article.
205 results