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Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Dolton G, Rius C, Wall A, Szomolay B, Bianchi V, Galloway SAE, Hasan MS, Morin T, Caillaud ME, Thomas HL, Theaker S, Tan LR, Fuller A, Topley K, Legut M, Attaf M, Hopkins JR, Behiry E, Zabkiewicz J, Alvares C, Lloyd A, Rogers A, Henley P, Fegan C, Ottmann O, Man S, Crowther MD, Donia M, Svane IM, Cole DK, Brown PE, Rizkallah P, Sewell AK. Dolton G, et al. Among authors: sewell ak. Cell. 2023 Aug 3;186(16):3333-3349.e27. doi: 10.1016/j.cell.2023.06.020. Epub 2023 Jul 24. Cell. 2023. PMID: 37490916 Free article.
Emergence of immune escape at dominant SARS-CoV-2 killer T cell epitope.
Dolton G, Rius C, Hasan MS, Wall A, Szomolay B, Behiry E, Whalley T, Southgate J, Fuller A; COVID-19 Genomics UK (COG-UK) consortium; Morin T, Topley K, Tan LR, Goulder PJR, Spiller OB, Rizkallah PJ, Jones LC, Connor TR, Sewell AK. Dolton G, et al. Among authors: sewell ak. Cell. 2022 Aug 4;185(16):2936-2951.e19. doi: 10.1016/j.cell.2022.07.002. Epub 2022 Jul 14. Cell. 2022. PMID: 35931021 Free PMC article.
Spatial, temporal and molecular dynamics of swine influenza virus-specific CD8 tissue resident memory T cells.
Martini V, Edmans M, Gubbins S, Jayaraman S, Paudyal B, Morgan S, McNee A, Morin T, Rijal P, Gerner W, Sewell AK, Inoue R, Bailey M, Connelley T, Charleston B, Townsend A, Beverley P, Tchilian E. Martini V, et al. Among authors: sewell ak. Mucosal Immunol. 2022 Mar;15(3):428-442. doi: 10.1038/s41385-021-00478-4. Epub 2022 Feb 10. Mucosal Immunol. 2022. PMID: 35145208 Free PMC article.
CD8 coreceptor-mediated focusing can reorder the agonist hierarchy of peptide ligands recognized via the T cell receptor.
Clement M, Knezevic L, Dockree T, McLaren JE, Ladell K, Miners KL, Llewellyn-Lacey S, Rubina A, Francis O, Cole DK, Sewell AK, Bridgeman JS, Price DA, van den Berg HA, Wooldridge L. Clement M, et al. Among authors: sewell ak. Proc Natl Acad Sci U S A. 2021 Jul 20;118(29):e2019639118. doi: 10.1073/pnas.2019639118. Proc Natl Acad Sci U S A. 2021. PMID: 34272276 Free PMC article.
208 results