Sevillano N - Search Results

1

Identification of recombinant Fabs for structural and functional characterization of HIV-host factor complexes.

Sevillano N, Green EM, Votteler J, Kim DY, Ren X, Yang B, Liu X, Lourenço AL, Hurley JH, Farr-Jones S, Gross JD, Cheng Y, Craik CS. Sevillano N, et al. PLoS One. 2021 May 13;16(5):e0250318. doi: 10.1371/journal.pone.0250318. eCollection 2021. PLoS One. 2021. PMID: 33983947 Free PMC article.

2

Fab-based inhibitors reveal ubiquitin independent functions for HIV Vif neutralization of APOBEC3 restriction factors.

Binning JM, Smith AM, Hultquist JF, Craik CS, Caretta Cartozo N, Campbell MG, Burton L, La Greca F, McGregor MJ, Ta HM, Bartholomeeusen K, Peterlin BM, Krogan NJ, Sevillano N, Cheng Y, Gross JD. Binning JM, et al. Among authors: sevillano n. PLoS Pathog. 2018 Jan 5;14(1):e1006830. doi: 10.1371/journal.ppat.1006830. eCollection 2018 Jan. PLoS Pathog. 2018. PMID: 29304101 Free PMC article.

3

Structure of an affinity-matured inhibitory recombinant fab against urokinase plasminogen activator reveals basis of potency and specificity.

Sevillano N, Bohn MF, Zimanyi M, Chen Y, Petzold C, Gupta S, Ralston CY, Craik CS. Sevillano N, et al. Biochim Biophys Acta Proteins Proteom. 2021 Feb;1869(2):140562. doi: 10.1016/j.bbapap.2020.140562. Epub 2020 Nov 19. Biochim Biophys Acta Proteins Proteom. 2021. PMID: 33221341 Free PMC article.

4

Site-Specific Radiofluorination of Biomolecules with 8-[(18)F]-Fluorooctanoic Acid Catalyzed by Lipoic Acid Ligase.

Drake CR, Sevillano N, Truillet C, Craik CS, VanBrocklin HF, Evans MJ. Drake CR, et al. Among authors: sevillano n. ACS Chem Biol. 2016 Jun 17;11(6):1587-94. doi: 10.1021/acschembio.6b00172. Epub 2016 Mar 31. ACS Chem Biol. 2016. PMID: 27008570 Free PMC article.

5

Discovery and Characterization of a Thioesterase-Specific Monoclonal Antibody That Recognizes the 6-Deoxyerythronolide B Synthase.

Li X, Sevillano N, La Greca F, Hsu J, Mathews II, Matsui T, Craik CS, Khosla C. Li X, et al. Among authors: sevillano n. Biochemistry. 2018 Oct 30;57(43):6201-6208. doi: 10.1021/acs.biochem.8b00886. Epub 2018 Oct 17. Biochemistry. 2018. PMID: 30289692 Free PMC article.

6

Antibody Probes of Module 1 of the 6-Deoxyerythronolide B Synthase Reveal an Extended Conformation During Ketoreduction.

Cogan DP, Li X, Sevillano N, Mathews II, Matsui T, Craik CS, Khosla C. Cogan DP, et al. Among authors: sevillano n. J Am Chem Soc. 2020 Sep 2;142(35):14933-14939. doi: 10.1021/jacs.0c05133. Epub 2020 Aug 18. J Am Chem Soc. 2020. PMID: 32786753 Free PMC article.

7

Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients.

Miller-Vedam LE, Bräuning B, Popova KD, Schirle Oakdale NT, Bonnar JL, Prabu JR, Boydston EA, Sevillano N, Shurtleff MJ, Stroud RM, Craik CS, Schulman BA, Frost A, Weissman JS. Miller-Vedam LE, et al. Among authors: sevillano n. Elife. 2020 Nov 25;9:e62611. doi: 10.7554/eLife.62611. Elife. 2020. PMID: 33236988 Free PMC article.

8

Structure-Function Analysis of the Extended Conformation of a Polyketide Synthase Module.

Li X, Sevillano N, La Greca F, Deis L, Liu YC, Deller MC, Mathews II, Matsui T, Cane DE, Craik CS, Khosla C. Li X, et al. Among authors: sevillano n. J Am Chem Soc. 2018 May 30;140(21):6518-6521. doi: 10.1021/jacs.8b02100. Epub 2018 May 18. J Am Chem Soc. 2018. PMID: 29762030 Free PMC article.

9

Imaging the urokinase plasminongen activator receptor in preclinical breast cancer models of acquired drug resistance.

LeBeau AM, Sevillano N, King ML, Duriseti S, Murphy ST, Craik CS, Murphy LL, VanBrocklin HF. LeBeau AM, et al. Among authors: sevillano n. Theranostics. 2014 Jan 18;4(3):267-79. doi: 10.7150/thno.7323. eCollection 2014. Theranostics. 2014. PMID: 24505235 Free PMC article.

10

Imaging active urokinase plasminogen activator in prostate cancer.

LeBeau AM, Sevillano N, Markham K, Winter MB, Murphy ST, Hostetter DR, West J, Lowman H, Craik CS, VanBrocklin HF. LeBeau AM, et al. Among authors: sevillano n. Cancer Res. 2015 Apr 1;75(7):1225-35. doi: 10.1158/0008-5472.CAN-14-2185. Epub 2015 Feb 11. Cancer Res. 2015. PMID: 25672980 Free PMC article.

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