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Novel penetrating cations for targeting mitochondria.
Chernyak BV, Antonenko YN, Domnina LV, Ivanova OY, Lyamzaev KG, Pustovidko AV, Rokitskaya TI, Severina II, Simonyan RA, Trendeleva TA, Zvyagilskaya RA. Chernyak BV, et al. Among authors: severina ii. Curr Pharm Des. 2013;19(15):2795-806. doi: 10.2174/1381612811319150015. Curr Pharm Des. 2013. PMID: 23092317 Review.
Novel mitochondria-targeted antioxidants: plastoquinone conjugated with cationic plant alkaloids berberine and palmatine.
Lyamzaev KG, Pustovidko AV, Simonyan RA, Rokitskaya TI, Domnina LV, Ivanova OY, Severina II, Sumbatyan NV, Korshunova GA, Tashlitsky VN, Roginsky VA, Antonenko YN, Skulachev MV, Chernyak BV, Skulachev VP. Lyamzaev KG, et al. Among authors: severina ii. Pharm Res. 2011 Nov;28(11):2883-95. doi: 10.1007/s11095-011-0504-8. Epub 2011 Jun 14. Pharm Res. 2011. PMID: 21671134
Derivatives of the cationic plant alkaloids berberine and palmatine amplify protonophorous activity of fatty acids in model membranes and mitochondria.
Pustovidko AV, Rokitskaya TI, Severina II, Simonyan RA, Trendeleva TA, Lyamzaev KG, Antonenko YN, Rogov AG, Zvyagilskaya RA, Skulachev VP, Chernyak BV. Pustovidko AV, et al. Among authors: severina ii. Mitochondrion. 2013 Sep;13(5):520-5. doi: 10.1016/j.mito.2012.09.006. Epub 2012 Sep 29. Mitochondrion. 2013. PMID: 23026390
In search of novel highly active mitochondria-targeted antioxidants: thymoquinone and its cationic derivatives.
Severina II, Severin FF, Korshunova GA, Sumbatyan NV, Ilyasova TM, Simonyan RA, Rogov AG, Trendeleva TA, Zvyagilskaya RA, Dugina VB, Domnina LV, Fetisova EK, Lyamzaev KG, Vyssokikh MY, Chernyak BV, Skulachev MV, Skulachev VP, Sadovnichii VA. Severina II, et al. FEBS Lett. 2013 Jun 27;587(13):2018-24. doi: 10.1016/j.febslet.2013.04.043. Epub 2013 May 10. FEBS Lett. 2013. PMID: 23665033 Free article. Review.
A short-chain alkyl derivative of Rhodamine 19 acts as a mild uncoupler of mitochondria and a neuroprotector.
Khailova LS, Silachev DN, Rokitskaya TI, Avetisyan AV, Lyamsaev KG, Severina II, Il'yasova TM, Gulyaev MV, Dedukhova VI, Trendeleva TA, Plotnikov EY, Zvyagilskaya RA, Chernyak BV, Zorov DB, Antonenko YN, Skulachev VP. Khailova LS, et al. Among authors: severina ii. Biochim Biophys Acta. 2014 Oct;1837(10):1739-47. doi: 10.1016/j.bbabio.2014.07.006. Epub 2014 Jul 16. Biochim Biophys Acta. 2014. PMID: 25038514 Free article.
Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 1. Cationic plastoquinone derivatives: synthesis and in vitro studies.
Antonenko YN, Avetisyan AV, Bakeeva LE, Chernyak BV, Chertkov VA, Domnina LV, Ivanova OY, Izyumov DS, Khailova LS, Klishin SS, Korshunova GA, Lyamzaev KG, Muntyan MS, Nepryakhina OK, Pashkovskaya AA, Pletjushkina OY, Pustovidko AV, Roginsky VA, Rokitskaya TI, Ruuge EK, Saprunova VB, Severina II, Simonyan RA, Skulachev IV, Skulachev MV, Sumbatyan NV, Sviryaeva IV, Tashlitsky VN, Vassiliev JM, Vyssokikh MY, Yaguzhinsky LS, Zamyatnin AA Jr, Skulachev VP. Antonenko YN, et al. Among authors: severina ii. Biochemistry (Mosc). 2008 Dec;73(12):1273-87. doi: 10.1134/s0006297908120018. Biochemistry (Mosc). 2008. PMID: 19120014 Free article.
Novel mitochondria-targeted compounds composed of natural constituents: conjugates of plant alkaloids berberine and palmatine with plastoquinone.
Chernyak BV, Antonenko YN, Galimov ER, Domnina LV, Dugina VB, Zvyagilskaya RA, Ivanova OY, Izyumov DS, Lyamzaev KG, Pustovidko AV, Rokitskaya TI, Rogov AG, Severina II, Simonyan RA, Skulachev MV, Tashlitsky VN, Titova EV, Trendeleva TA, Shagieva GS. Chernyak BV, et al. Among authors: severina ii. Biochemistry (Mosc). 2012 Sep;77(9):983-95. doi: 10.1134/S0006297912090040. Biochemistry (Mosc). 2012. PMID: 23157257 Free article. Review.
45 results