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Transglutaminase Type 2-MITF axis regulates phenotype switching in skin cutaneous melanoma.
Muccioli S, Brillo V, Varanita T, Rossin F, Zaltron E, Velle A, Alessio G, Angi B, Severin F, Tosi A, D'Eletto M, Occhigrossi L, Falasca L, Checchetto V, Ciaccio R, Fascì A, Chieregato L, Rebelo AP, Giacomello M, Rosato A, Szabò I, Romualdi C, Piacentini M, Leanza L. Muccioli S, et al. Among authors: severin f. Cell Death Dis. 2023 Oct 28;14(10):704. doi: 10.1038/s41419-023-06223-y. Cell Death Dis. 2023. PMID: 37898636 Free PMC article.
Pharmacological modulation of Kv1.3 potassium channel selectively triggers pathological B lymphocyte apoptosis in vivo in a genetic CLL model.
Severin F, Urbani A, Varanita T, Bachmann M, Azzolini M, Martini V, Pizzi M, Tos APD, Frezzato F, Mattarei A, Ghia P, Bertilaccio MTS, Gulbins E, Paradisi C, Zoratti M, Semenzato GC, Leanza L, Trentin L, Szabò I. Severin F, et al. J Exp Clin Cancer Res. 2022 Feb 16;41(1):64. doi: 10.1186/s13046-022-02249-w. J Exp Clin Cancer Res. 2022. PMID: 35172855 Free PMC article.
The Role of Transglutaminase 2 in Cancer: An Update.
Zaltron E, Vianello F, Ruzza A, Palazzo A, Brillo V, Celotti I, Scavezzon M, Rossin F, Leanza L, Severin F. Zaltron E, et al. Among authors: severin f. Int J Mol Sci. 2024 Feb 28;25(5):2797. doi: 10.3390/ijms25052797. Int J Mol Sci. 2024. PMID: 38474044 Free PMC article. Review.
Direct Pharmacological Targeting of a Mitochondrial Ion Channel Selectively Kills Tumor Cells In Vivo.
Leanza L, Romio M, Becker KA, Azzolini M, Trentin L, Managò A, Venturini E, Zaccagnino A, Mattarei A, Carraretto L, Urbani A, Kadow S, Biasutto L, Martini V, Severin F, Peruzzo R, Trimarco V, Egberts JH, Hauser C, Visentin A, Semenzato G, Kalthoff H, Zoratti M, Gulbins E, Paradisi C, Szabo I. Leanza L, et al. Among authors: severin f. Cancer Cell. 2017 Apr 10;31(4):516-531.e10. doi: 10.1016/j.ccell.2017.03.003. Cancer Cell. 2017. PMID: 28399409 Free article.
Lights and Shade of Next-Generation Pi3k Inhibitors in Chronic Lymphocytic Leukemia.
Visentin A, Frezzato F, Severin F, Imbergamo S, Pravato S, Romano Gargarella L, Manni S, Pizzo S, Ruggieri E, Facco M, Brunati AM, Semenzato G, Piazza F, Trentin L. Visentin A, et al. Among authors: severin f. Onco Targets Ther. 2020 Sep 29;13:9679-9688. doi: 10.2147/OTT.S268899. eCollection 2020. Onco Targets Ther. 2020. PMID: 33061448 Free PMC article. Review.
In Chronic Lymphocytic Leukemia the JAK2/STAT3 Pathway Is Constitutively Activated and Its Inhibition Leads to CLL Cell Death Unaffected by the Protective Bone Marrow Microenvironment.
Severin F, Frezzato F, Visentin A, Martini V, Trimarco V, Carraro S, Tibaldi E, Brunati AM, Piazza F, Semenzato G, Facco M, Trentin L. Severin F, et al. Cancers (Basel). 2019 Dec 4;11(12):1939. doi: 10.3390/cancers11121939. Cancers (Basel). 2019. PMID: 31817171 Free PMC article.
Targeting of HSP70/HSF1 Axis Abrogates In Vitro Ibrutinib-Resistance in Chronic Lymphocytic Leukemia.
Frezzato F, Visentin A, Severin F, Pizzo S, Ruggeri E, Mouawad N, Martinello L, Pagnin E, Trimarco V, Tonini A, Carraro S, Pravato S, Imbergamo S, Manni S, Piazza F, Brunati AM, Facco M, Trentin L. Frezzato F, et al. Among authors: severin f. Cancers (Basel). 2021 Oct 29;13(21):5453. doi: 10.3390/cancers13215453. Cancers (Basel). 2021. PMID: 34771616 Free PMC article.
161 results