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Naphthyl tetronic acids as multi-target inhibitors of bacterial peptidoglycan biosynthesis.
Mansour TS, Caufield CE, Rasmussen B, Chopra R, Krishnamurthy G, Morris KM, Svenson K, Bard J, Smeltzer C, Naughton S, Antane S, Yang Y, Severin A, Quagliato D, Petersen PJ, Singh G. Mansour TS, et al. Among authors: severin a. ChemMedChem. 2007 Oct;2(10):1414-7. doi: 10.1002/cmdc.200700094. ChemMedChem. 2007. PMID: 17600795 No abstract available.
3,5-dioxopyrazolidines, novel inhibitors of UDP-N- acetylenolpyruvylglucosamine reductase (MurB) with activity against gram-positive bacteria.
Yang Y, Severin A, Chopra R, Krishnamurthy G, Singh G, Hu W, Keeney D, Svenson K, Petersen PJ, Labthavikul P, Shlaes DM, Rasmussen BA, Failli AA, Shumsky JS, Kutterer KM, Gilbert A, Mansour TS. Yang Y, et al. Among authors: severin a. Antimicrob Agents Chemother. 2006 Feb;50(2):556-64. doi: 10.1128/AAC.50.2.556-564.2006. Antimicrob Agents Chemother. 2006. PMID: 16436710 Free PMC article.
Mechanism of action of the mannopeptimycins, a novel class of glycopeptide antibiotics active against vancomycin-resistant gram-positive bacteria.
Ruzin A, Singh G, Severin A, Yang Y, Dushin RG, Sutherland AG, Minnick A, Greenstein M, May MK, Shlaes DM, Bradford PA. Ruzin A, et al. Among authors: severin a. Antimicrob Agents Chemother. 2004 Mar;48(3):728-38. doi: 10.1128/AAC.48.3.728-738.2004. Antimicrob Agents Chemother. 2004. PMID: 14982757 Free PMC article.
170 results