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Organ Protection by Caloric Restriction Depends on Activation of the De Novo NAD+ Synthesis Pathway.
Späth MR, Hoyer-Allo KJR, Seufert L, Höhne M, Lucas C, Bock T, Isermann L, Brodesser S, Lackmann JW, Kiefer K, Koehler FC, Bohl K, Ignarski M, Schiller P, Johnsen M, Kubacki T, Grundmann F, Benzing T, Trifunovic A, Krüger M, Schermer B, Burst V, Müller RU. Späth MR, et al. Among authors: seufert l. J Am Soc Nephrol. 2023 May 1;34(5):772-792. doi: 10.1681/ASN.0000000000000087. Epub 2023 Feb 9. J Am Soc Nephrol. 2023. PMID: 36758124 Free PMC article.
RNA-binding proteins and their role in kidney disease.
Seufert L, Benzing T, Ignarski M, Müller RU. Seufert L, et al. Nat Rev Nephrol. 2022 Mar;18(3):153-170. doi: 10.1038/s41581-021-00497-1. Epub 2021 Nov 3. Nat Rev Nephrol. 2022. PMID: 34732838 Review.
Caloric restriction reduces the pro-inflammatory eicosanoid 20-hydroxyeicosatetraenoic acid to protect from acute kidney injury.
Hoyer-Allo KJR, Späth MR, Brodesser S, Zhu Y, Binz-Lotter J, Höhne M, Brönneke H, Bohl K, Johnsen M, Kubacki T, Kiefer K, Seufert L, Koehler FC, Grundmann F, Hackl MJ, Schermer B, Brüning J, Benzing T, Burst V, Müller RU. Hoyer-Allo KJR, et al. Among authors: seufert l. Kidney Int. 2022 Sep;102(3):560-576. doi: 10.1016/j.kint.2022.04.033. Epub 2022 May 30. Kidney Int. 2022. PMID: 35654224
A protein-RNA interaction atlas of the ribosome biogenesis factor AATF.
Kaiser RWJ, Ignarski M, Van Nostrand EL, Frese CK, Jain M, Cukoski S, Heinen H, Schaechter M, Seufert L, Bunte K, Frommolt P, Keller P, Helm M, Bohl K, Höhne M, Schermer B, Benzing T, Höpker K, Dieterich C, Yeo GW, Müller RU, Fabretti F. Kaiser RWJ, et al. Among authors: seufert l. Sci Rep. 2019 Jul 30;9(1):11071. doi: 10.1038/s41598-019-47552-3. Sci Rep. 2019. PMID: 31363146 Free PMC article.