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T cell activation is insufficient to drive SIV disease progression.
Apetrei C, Gaufin T, Brocca-Cofano E, Sivanandham R, Sette P, He T, Sivanandham S, Martinez Sosa N, Martin KJ, Raehtz KD, Kleinman AJ, Valentine A, Krampe N, Gautam R, Lackner AA, Landay AL, Ribeiro RM, Pandrea I. Apetrei C, et al. Among authors: sette p. JCI Insight. 2023 Jul 24;8(14):e161111. doi: 10.1172/jci.insight.161111. JCI Insight. 2023. PMID: 37485874 Free PMC article.
High-fat diet exacerbates SIV pathogenesis and accelerates disease progression.
He T, Xu C, Krampe N, Dillon SM, Sette P, Falwell E, Haret-Richter GS, Butterfield T, Dunsmore TL, McFadden WM Jr, Martin KJ, Policicchio BB, Raehtz KD, Penn EP, Tracy RP, Ribeiro RM, Frank DN, Wilson CC, Landay AL, Apetrei C, Pandrea I. He T, et al. Among authors: sette p. J Clin Invest. 2019 Dec 2;129(12):5474-5488. doi: 10.1172/JCI121208. J Clin Invest. 2019. PMID: 31710311 Free PMC article.
Nonhuman Primate Testing of the Impact of Different Regulatory T Cell Depletion Strategies on Reactivation and Clearance of Latent Simian Immunodeficiency Virus.
Sivanandham R, Kleinman AJ, Sette P, Brocca-Cofano E, Kilapandal Venkatraman SM, Policicchio BB, He T, Xu C, Swarthout J, Wang Z, Pandrea I, Apetrei C. Sivanandham R, et al. Among authors: sette p. J Virol. 2020 Sep 15;94(19):e00533-20. doi: 10.1128/JVI.00533-20. Print 2020 Sep 15. J Virol. 2020. PMID: 32669326 Free PMC article.
Lack of Specific Regulatory T Cell Depletion and Cytoreduction Associated with Extensive Toxicity After Administration of Low and High Doses of Cyclophosphamide.
Kleinman AJ, Sivanandham R, Sette P, Brocca-Cofano E, McAndrews C, Keele BF, Pandrea I, Apetrei C. Kleinman AJ, et al. Among authors: sette p. AIDS Res Hum Retroviruses. 2022 Jan;38(1):45-49. doi: 10.1089/AID.2021.0036. Epub 2021 Jun 8. AIDS Res Hum Retroviruses. 2022. PMID: 33957772 Free PMC article.
Changes to the Simian Immunodeficiency Virus (SIV) Reservoir and Enhanced SIV-Specific Responses in a Rhesus Macaque Model of Functional Cure after Serial Rounds of Romidepsin Administrations.
Kleinman AJ, Sivanandham S, Sette P, Sivanandham R, Policicchio BB, Xu C, Penn E, Brocca-Cofano E, Le Hingrat Q, Ma D, Pandrea I, Apetrei C. Kleinman AJ, et al. Among authors: sette p. J Virol. 2022 Jun 22;96(12):e0044522. doi: 10.1128/jvi.00445-22. Epub 2022 May 31. J Virol. 2022. PMID: 35638831 Free PMC article.
Prolonged experimental CD4+ T-cell depletion does not cause disease progression in SIV-infected African green monkeys.
Le Hingrat Q, Sette P, Xu C, Rahmberg AR, Tarnus L, Annapureddy H, Kleinman A, Brocca-Cofano E, Sivanandham R, Sivanandham S, He T, Capreri DJ, Ma D, Estes JD, Brenchley JM, Apetrei C, Pandrea I. Le Hingrat Q, et al. Among authors: sette p. Nat Commun. 2023 Feb 22;14(1):979. doi: 10.1038/s41467-023-36379-2. Nat Commun. 2023. PMID: 36813761 Free PMC article.
101 results