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Memory T cells effectively recognize the SARS-CoV-2 hypermutated BA.2.86 variant.
Müller TR, Gao Y, Wu J, Ribeiro O, Chen P, Bergman P, Blennow O, Hansson L, Mielke S, Nowak P, Vesterbacka J, Akber M, Söderdahl G, Smith CIE, Loré K, Chen MS, Ljungman P, Ingelman-Sundberg HM, Ljunggren HG, Österborg A, Sette A, Grifoni A, Aleman S, Buggert M. Müller TR, et al. Among authors: sette a. Cell Host Microbe. 2024 Feb 14;32(2):156-161.e3. doi: 10.1016/j.chom.2023.12.010. Epub 2024 Jan 10. Cell Host Microbe. 2024. PMID: 38211584 Free article.
mRNA Vaccination Induces Durable Immune Memory to SARS-CoV-2 with Continued Evolution to Variants of Concern.
Goel RR, Painter MM, Apostolidis SA, Mathew D, Meng W, Rosenfeld AM, Lundgreen KA, Reynaldi A, Khoury DS, Pattekar A, Gouma S, Kuri-Cervantes L, Hicks P, Dysinger S, Hicks A, Sharma H, Herring S, Korte S, Baxter AE, Oldridge DA, Giles JR, Weirick ME, McAllister CM, Awofolaju M, Tanenbaum N, Drapeau EM, Dougherty J, Long S, D'Andrea K, Hamilton JT, McLaughlin M, Williams JC, Adamski S, Kuthuru O; UPenn COVID Processing Unit; Frank I, Betts MR, Vella LA, Grifoni A, Weiskopf D, Sette A, Hensley SE, Davenport MP, Bates P, Luning Prak ET, Greenplate AR, Wherry EJ. Goel RR, et al. Among authors: sette a. bioRxiv [Preprint]. 2021 Aug 23:2021.08.23.457229. doi: 10.1101/2021.08.23.457229. bioRxiv. 2021. PMID: 34462751 Free PMC article. Updated. Preprint.
Humoral and cellular immune responses to CoronaVac assessed up to one year after vaccination.
Costa PR, Correia CA, Marmorato MP, de Carvalho Dias JZ, Thomazella MV, da Silva AC, de Oliveira ACS, Gusmão AF, Ferrari L, Freitas AC, Patiño EG, Grifoni A, Weiskopf D, Sette A, Scharf R, Kallas EG, Terrassani Silveira CG. Costa PR, et al. Among authors: sette a. medRxiv [Preprint]. 2022 Jul 7:2022.03.16.22272513. doi: 10.1101/2022.03.16.22272513. medRxiv. 2022. PMID: 35821982 Free PMC article. Updated. Preprint.
Targets and cross-reactivity of human T cell recognition of Common Cold Coronaviruses.
Tarke A, Zhang Y, Methot N, Narowski TM, Phillips E, Mallal S, Frazier A, Filaci G, Weiskopf D, Dan JM, Premkumar L, Scheuermann RH, Sette A, Grifoni A. Tarke A, et al. Among authors: sette a. bioRxiv [Preprint]. 2023 Jan 5:2023.01.04.522794. doi: 10.1101/2023.01.04.522794. bioRxiv. 2023. PMID: 36656777 Free PMC article. Updated. Preprint.
Post-pandemic memory T cell response to SARS-CoV-2 is durable, broadly targeted, and cross-reactive to the hypermutated BA.2.86 variant.
Nesamari R, Omondi MA, Baguma R, Höft MA, Ngomti A, Nkayi AA, Besethi AS, Magugu SFJ, Mosala P, Walters A, Clark GM, Mennen M, Skelem S, Adriaanse M, Grifoni A, Sette A, Keeton RS, Ntusi NAB, Riou C, Burgers WA. Nesamari R, et al. Among authors: sette a. Cell Host Microbe. 2024 Feb 14;32(2):162-169.e3. doi: 10.1016/j.chom.2023.12.003. Epub 2024 Jan 10. Cell Host Microbe. 2024. PMID: 38211583 Free PMC article.
Combined antiviral therapy as effective and feasible option in allogenic hematopoietic stem cell transplantation during SARS-COV-2 infection: a case report.
Vita S, D'Abramo A, Coppola A, Farroni C, Iori AP, Faraglia F, Sette A, Grifoni A, Lindestam Arlehamn C, Bibas M, Goletti D, Nicastri E. Vita S, et al. Among authors: sette a. Front Oncol. 2024 Feb 13;14:1290614. doi: 10.3389/fonc.2024.1290614. eCollection 2024. Front Oncol. 2024. PMID: 38414746 Free PMC article.
Early antiviral CD4 and CD8 T cell responses are associated with upper respiratory tract clearance of SARS-CoV-2.
Ramirez SI, Lopez PG, Faraji F, Parikh UM, Heaps A, Ritz J, Moser C, Eron JJ, Wohl DA, Currier JS, Daar ES, Greninger AL, Klekotka P, Grifoni A, Weiskopf D, Sette A, Peters B, Hughes MD, Chew KW, Smith DM, Crotty S; ACTIV-2/A5401 Study Team. Ramirez SI, et al. Among authors: sette a. bioRxiv [Preprint]. 2023 Oct 26:2023.10.25.564014. doi: 10.1101/2023.10.25.564014. bioRxiv. 2023. PMID: 37961119 Free PMC article. Preprint.
Safety, tolerability, viral kinetics, and immune correlates of protection in healthy, seropositive UK adults inoculated with SARS-CoV-2: a single-centre, open-label, phase 1 controlled human infection study.
Jackson S, Marshall JL, Mawer A, Lopez-Ramon R, Harris SA, Satti I, Hughes E, Preston-Jones H, Cabrera Puig I, Longet S, Tipton T, Laidlaw S, Doherty RP, Morrison H, Mitchell R, Tanner R, Ateere A, Stylianou E, Wu MS, Fredsgaard-Jones TPW, Breuer J, Rapeport G, Ferreira VM, Gleeson F, Pollard AJ, Carroll M, Catchpole A, Chiu C, McShane H; COV-CHIM01 study team. Jackson S, et al. Lancet Microbe. 2024 Apr 26:S2666-5247(24)00025-9. doi: 10.1016/S2666-5247(24)00025-9. Online ahead of print. Lancet Microbe. 2024. PMID: 38703782 Free article.
1,095 results