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DEAD-box helicase DP103 defines metastatic potential of human breast cancers.
Shin EM, Hay HS, Lee MH, Goh JN, Tan TZ, Sen YP, Lim SW, Yousef EM, Ong HT, Thike AA, Kong X, Wu Z, Mendoz E, Sun W, Salto-Tellez M, Lim CT, Lobie PE, Lim YP, Yap CT, Zeng Q, Sethi G, Lee MB, Tan P, Goh BC, Miller LD, Thiery JP, Zhu T, Gaboury L, Tan PH, Hui KM, Yip GW, Miyamoto S, Kumar AP, Tergaonkar V. Shin EM, et al. Among authors: sethi g. J Clin Invest. 2014 Sep;124(9):3807-24. doi: 10.1172/JCI73451. Epub 2014 Aug 1. J Clin Invest. 2014. PMID: 25083991 Free PMC article.
Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3.
Dai X, Ahn KS, Kim C, Siveen KS, Ong TH, Shanmugam MK, Li F, Shi J, Kumar AP, Wang LZ, Goh BC, Magae J, Hui KM, Sethi G. Dai X, et al. Among authors: sethi g. Mol Oncol. 2015 Apr;9(4):818-33. doi: 10.1016/j.molonc.2014.12.008. Epub 2015 Jan 5. Mol Oncol. 2015. PMID: 25624051 Free PMC article.
Targeting transcription factor STAT3 for cancer prevention and therapy.
Chai EZ, Shanmugam MK, Arfuso F, Dharmarajan A, Wang C, Kumar AP, Samy RP, Lim LH, Wang L, Goh BC, Ahn KS, Hui KM, Sethi G. Chai EZ, et al. Among authors: sethi g. Pharmacol Ther. 2016 Jun;162:86-97. doi: 10.1016/j.pharmthera.2015.10.004. Epub 2016 Feb 12. Pharmacol Ther. 2016. PMID: 26478441 Review.
Nimbolide-Induced Oxidative Stress Abrogates STAT3 Signaling Cascade and Inhibits Tumor Growth in Transgenic Adenocarcinoma of Mouse Prostate Model.
Zhang J, Ahn KS, Kim C, Shanmugam MK, Siveen KS, Arfuso F, Samym RP, Deivasigamanim A, Lim LH, Wang L, Goh BC, Kumar AP, Hui KM, Sethi G. Zhang J, et al. Among authors: sethi g. Antioxid Redox Signal. 2016 Apr 10;24(11):575-89. doi: 10.1089/ars.2015.6418. Epub 2016 Jan 26. Antioxid Redox Signal. 2016. PMID: 26649526
Cancer prevention and therapy through the modulation of transcription factors by bioactive natural compounds.
Shanmugam MK, Lee JH, Chai EZ, Kanchi MM, Kar S, Arfuso F, Dharmarajan A, Kumar AP, Ramar PS, Looi CY, Mustafa MR, Tergaonkar V, Bishayee A, Ahn KS, Sethi G. Shanmugam MK, et al. Among authors: sethi g. Semin Cancer Biol. 2016 Oct;40-41:35-47. doi: 10.1016/j.semcancer.2016.03.005. Epub 2016 Mar 30. Semin Cancer Biol. 2016. PMID: 27038646 Review.
900 results