Sethi G - Search Results

1

FBXW7 in Cancer: What Has Been Unraveled Thus Far?

Sailo BL, Banik K, Girisa S, Bordoloi D, Fan L, Halim CE, Wang H, Kumar AP, Zheng D, Mao X, Sethi G, Kunnumakkara AB. Sailo BL, et al. Among authors: sethi g. Cancers (Basel). 2019 Feb 19;11(2):246. doi: 10.3390/cancers11020246. Cancers (Basel). 2019. PMID: 30791487 Free PMC article. Review.

2

Overexpression of tissue transglutaminase leads to constitutive activation of nuclear factor-kappaB in cancer cells: delineation of a novel pathway.

Mann AP, Verma A, Sethi G, Manavathi B, Wang H, Fok JY, Kunnumakkara AB, Kumar R, Aggarwal BB, Mehta K. Mann AP, et al. Among authors: sethi g. Cancer Res. 2006 Sep 1;66(17):8788-95. doi: 10.1158/0008-5472.CAN-06-1457. Cancer Res. 2006. PMID: 16951195

3

Deguelin, an Akt inhibitor, suppresses IkappaBalpha kinase activation leading to suppression of NF-kappaB-regulated gene expression, potentiation of apoptosis, and inhibition of cellular invasion.

Nair AS, Shishodia S, Ahn KS, Kunnumakkara AB, Sethi G, Aggarwal BB. Nair AS, et al. Among authors: sethi g. J Immunol. 2006 Oct 15;177(8):5612-22. doi: 10.4049/jimmunol.177.8.5612. J Immunol. 2006. PMID: 17015749

4

Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solution.

Aggarwal BB, Sethi G, Ahn KS, Sandur SK, Pandey MK, Kunnumakkara AB, Sung B, Ichikawa H. Aggarwal BB, et al. Among authors: sethi g. Ann N Y Acad Sci. 2006 Dec;1091:151-69. doi: 10.1196/annals.1378.063. Ann N Y Acad Sci. 2006. PMID: 17341611 Review.

5

Butein, a tetrahydroxychalcone, inhibits nuclear factor (NF)-kappaB and NF-kappaB-regulated gene expression through direct inhibition of IkappaBalpha kinase beta on cysteine 179 residue.

Pandey MK, Sandur SK, Sung B, Sethi G, Kunnumakkara AB, Aggarwal BB. Pandey MK, et al. Among authors: sethi g. J Biol Chem. 2007 Jun 15;282(24):17340-50. doi: 10.1074/jbc.M700890200. Epub 2007 Apr 17. J Biol Chem. 2007. PMID: 17439942 Free article.

6

Capsaicin is a novel blocker of constitutive and interleukin-6-inducible STAT3 activation.

Bhutani M, Pathak AK, Nair AS, Kunnumakkara AB, Guha S, Sethi G, Aggarwal BB. Bhutani M, et al. Among authors: sethi g. Clin Cancer Res. 2007 May 15;13(10):3024-32. doi: 10.1158/1078-0432.CCR-06-2575. Clin Cancer Res. 2007. PMID: 17505005

7

Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis.

Pandey MK, Sung B, Kunnumakkara AB, Sethi G, Chaturvedi MM, Aggarwal BB. Pandey MK, et al. Among authors: sethi g. Cancer Res. 2008 Jul 1;68(13):5370-9. doi: 10.1158/0008-5472.CAN-08-0511. Cancer Res. 2008. PMID: 18593939

8

SH-5, an AKT inhibitor potentiates apoptosis and inhibits invasion through the suppression of anti-apoptotic, proliferative and metastatic gene products regulated by IkappaBalpha kinase activation.

Sethi G, Ahn KS, Sung B, Kunnumakkara AB, Chaturvedi MM, Aggarwal BB. Sethi G, et al. Biochem Pharmacol. 2008 Dec 1;76(11):1404-16. doi: 10.1016/j.bcp.2008.05.023. Epub 2008 Jul 5. Biochem Pharmacol. 2008. PMID: 18606397

9

Targeting TNF for Treatment of Cancer and Autoimmunity.

Sethi G, Sung B, Kunnumakkara AB, Aggarwal BB. Sethi G, et al. Adv Exp Med Biol. 2009;647:37-51. doi: 10.1007/978-0-387-89520-8_3. Adv Exp Med Biol. 2009. PMID: 19760065 Review.

10

Identification of beta-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells.

Tan SM, Li F, Rajendran P, Kumar AP, Hui KM, Sethi G. Tan SM, et al. Among authors: sethi g. J Pharmacol Exp Ther. 2010 Jul;334(1):285-93. doi: 10.1124/jpet.110.165498. Epub 2010 Apr 8. J Pharmacol Exp Ther. 2010. PMID: 20378717

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