Sethi G - Search Results

1

Molecular targets and anti-cancer potential of escin.

Cheong DHJ, Arfuso F, Sethi G, Wang L, Hui KM, Kumar AP, Tran T. Cheong DHJ, et al. Among authors: sethi g. Cancer Lett. 2018 May 28;422:1-8. doi: 10.1016/j.canlet.2018.02.027. Epub 2018 Feb 21. Cancer Lett. 2018. PMID: 29474858 Review.

2

Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells.

Li F, Fernandez PP, Rajendran P, Hui KM, Sethi G. Li F, et al. Among authors: sethi g. Cancer Lett. 2010 Jun 28;292(2):197-207. doi: 10.1016/j.canlet.2009.12.003. Epub 2010 Jan 6. Cancer Lett. 2010. PMID: 20053498

3

Identification of beta-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells.

Tan SM, Li F, Rajendran P, Kumar AP, Hui KM, Sethi G. Tan SM, et al. Among authors: sethi g. J Pharmacol Exp Ther. 2010 Jul;334(1):285-93. doi: 10.1124/jpet.110.165498. Epub 2010 Apr 8. J Pharmacol Exp Ther. 2010. PMID: 20378717

4

Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-κB activation in breast and pancreatic tumor cells.

Chua AW, Hay HS, Rajendran P, Shanmugam MK, Li F, Bist P, Koay ES, Lim LH, Kumar AP, Sethi G. Chua AW, et al. Among authors: sethi g. Biochem Pharmacol. 2010 Nov 15;80(10):1553-62. doi: 10.1016/j.bcp.2010.07.045. Epub 2010 Aug 10. Biochem Pharmacol. 2010. PMID: 20699088

5

Suppression of signal transducer and activator of transcription 3 activation by butein inhibits growth of human hepatocellular carcinoma in vivo.

Rajendran P, Ong TH, Chen L, Li F, Shanmugam MK, Vali S, Abbasi T, Kapoor S, Sharma A, Kumar AP, Hui KM, Sethi G. Rajendran P, et al. Among authors: sethi g. Clin Cancer Res. 2011 Mar 15;17(6):1425-39. doi: 10.1158/1078-0432.CCR-10-1123. Epub 2010 Dec 3. Clin Cancer Res. 2011. PMID: 21131551

6

Molecular targets of celastrol derived from Thunder of God Vine: potential role in the treatment of inflammatory disorders and cancer.

Kannaiyan R, Shanmugam MK, Sethi G. Kannaiyan R, et al. Among authors: sethi g. Cancer Lett. 2011 Apr 1;303(1):9-20. doi: 10.1016/j.canlet.2010.10.025. Epub 2010 Dec 17. Cancer Lett. 2011. PMID: 21168266 Review.

7

γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent.

Rajendran P, Li F, Manu KA, Shanmugam MK, Loo SY, Kumar AP, Sethi G. Rajendran P, et al. Among authors: sethi g. Br J Pharmacol. 2011 May;163(2):283-98. doi: 10.1111/j.1476-5381.2010.01187.x. Br J Pharmacol. 2011. PMID: 21198544 Free PMC article.

8

Targeting cell signaling and apoptotic pathways by dietary agents: role in the prevention and treatment of cancer.

Shanmugam MK, Kannaiyan R, Sethi G. Shanmugam MK, et al. Among authors: sethi g. Nutr Cancer. 2011;63(2):161-73. doi: 10.1080/01635581.2011.523502. Nutr Cancer. 2011. PMID: 21294053 Review.

9

Ursolic acid inhibits multiple cell survival pathways leading to suppression of growth of prostate cancer xenograft in nude mice.

Shanmugam MK, Rajendran P, Li F, Nema T, Vali S, Abbasi T, Kapoor S, Sharma A, Kumar AP, Ho PC, Hui KM, Sethi G. Shanmugam MK, et al. Among authors: sethi g. J Mol Med (Berl). 2011 Jul;89(7):713-27. doi: 10.1007/s00109-011-0746-2. Epub 2011 Apr 5. J Mol Med (Berl). 2011. PMID: 21465181

10

Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model.

Shanmugam MK, Manu KA, Ong TH, Ramachandran L, Surana R, Bist P, Lim LH, Kumar AP, Hui KM, Sethi G. Shanmugam MK, et al. Among authors: sethi g. Int J Cancer. 2011 Oct 1;129(7):1552-63. doi: 10.1002/ijc.26120. Epub 2011 Jul 20. Int J Cancer. 2011. PMID: 21480220 Free article.

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